Ossifying Fibroma of the Jaws: A Clinicopathological Case Series Study

Abstract

were reviewed. Clinical data were obtained from the patient files and the radiographic features were evaluated in each case. All cases were reviewed microscopically to confirm the diagnosis. Eight cases were identified, 5 in females and 3 in males. The mean age of the patients was 33.7 years and most lesions (7 cases) occurred in the mandible. Radiographically, all lesions appeared as unilocular images and most of them (5 cases) were of mixed type. The mean size of the tumor was 3.1 cm and 3 cases caused displacement of the involved teeth. Microscopically, all cases showed several bone-like mineralized areas, immersed in the cellular connective tissue. From the 8 cases, 5 underwent surgical excision and 1 patient refused treatment. In the remaining 2 cases, this information was not available. In conclusion, OF occurs more commonly in women in the fourth decade of life, frequently as a mixed radiographic image in the mandible. Coherent differential diagnoses are important to guide the most adequate clinical approach. A correlation between clinical, imaginological and histopathological features is the key to establish the correct diagnosis.

Gnathic Bones and Hyperparathyroidism: A Review on the Metabolic Bony Changes Affecting the Mandible and Maxilla in case of Hyperparathyroidism

“…Radiopaque lesions include fibrous dysplasia complex odontoma, idiopathic osteosclerosis, and cementoblastoma. Mixed lesions include osteoblastoma, calcifying cystic odontogenic tumor, and calcifying epithelial odontogenic tumor [68].…”

Ossifying fibroma: an uncommon differential diagnosis for T2-hypointense sinonasal masses

“…It occurs most commonly in the mandible of female patients during the third and fourth decades of life [1].…”

“…Ossifying fibroma (OF) is considered a rare benign fibro-osseous lesion that occurs most commonly in female patients during the third and fourth decades of life [1]. It mainly involves the mandibular and maxillary bones, although in rare cases it may develop within the nasal cavity or in long bones [2].…”

Ossifying Fibroma of the Mandible

“…The previously used term cemento-ossifying fibroma was renamed as ossifying fibroma according to the revised WHO classification (2005) [1,2]. It is thought that ossifying fibromas of the jaw arise from the periodontal ligament but this remains controversial as similar lesions may appear in bones that lack this structure.…”