Ossified metaplastic meningiomas: A systematic review on a rare subset of “brain stones”

Paolini, Federica; Scalia, Gianluca; Graziano, Francesca; Umana, Giuseppe Emmanuele; Maugeri, Rosario; Iacopino, Domenico Gerardo; Nicoletti, Giovanni Federico

doi:10.1016/j.bas.2022.101189

Cited by 2 publications

(1 citation statement)

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“…Metaplastic meningioma is a kind of benign tumor originating from arachnoid epithelial cells, which can differentiate into mesenchymal tissues including the bone, cartilage, smooth muscle, and adipose tissues alone or in combination. Most of them grow slowly with a pathological grade of WHO 1, and their clinical symptoms mainly depend on the location of the tumor ( 16 , 17 ). There is a clear difference between meningiomas ossification and calcification.…”

Section: Discussionmentioning

confidence: 99%

Multiple ossified intracranial and spinal meningiomas: a rare case report and literature review

Wang,

Zhang,

Wang

et al. 2023

Front. Neurol.

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Ossified intracranial meningiomas (OIM) and ossified spinal meningiomas (OSM) are rare neoplasms of mesenchymal origin that predominantly manifest in the spinal cord and infrequently in the cranial region, accounting for ~0. 7–5.5% of all meningiomas. It is extremely rare to have multiple intracranial and spinal lesions accompanied by ossification. Herein, we report this rare case for the first time. A 34-year-old woman presented with paresthesia and limb weakness in the right lower limb and gradually worsened. Approximately half a year later, she could only walk with crutches. Magnetic resonance imaging of the brain and spinal cord showed multiple meningiomas, and histopathological examination confirmed multiple OIM and OSM (WHO grade 1). Multiple OIM and OSM are extremely rare with diverse imaging features, and it is easily confused with other tumors. Histopathological examination is the final diagnostic method.

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Section: Discussionmentioning

confidence: 99%