Osseous integration of bovine hydroxyapatite ceramic in metaphyseal bone defects of the distal radius

Werber, K. D.; Brauer, Robert B.; Weiß, Wolfgang; Becker, Karen

doi:10.1053/jhsu.2000.16354

Cited by 38 publications

(19 citation statements)

References 27 publications

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“…Calcium phosphate bone substitutes are available as granules, blocks, or injectable cements [5]. Although HA and TCP blocks and granules have been successfully applied in metaphyseal cancellous bone defects in the distal radius, tibial plateau, and calcaneus [21,22], injectable calcium phosphate bone cements with compressive strength similar to cancellous bone promise better bone defect filling and earlier full weight-bearing of the bony injury [8,12,23].…”

Section: Discussionmentioning

confidence: 99%

“…Many reports about successful application of bone substitutes exist [8,12,21,[26][27][28][29]; however, in particular cases, excessive inflammatory reactions were noticed. This sporadically led to damage of the surrounding soft tissue, implant failure, and infection [7, 9-11, 30, 31]; therefore, our study tries to find out if there is coherence between implant failure and the type of used material.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Microvascular response to calcium phosphate bone substitutes: an intravital microscopy analysis

Roetman

Ring

Langer

et al. 2010

Langenbecks Arch Surg

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Microvascular response to calcium phosphate bone substitutes: an intravital microscopy analysis

Roetman

Ring

Langer

et al. 2010

Langenbecks Arch Surg

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“…HA ceramic Endobon Ò can be used to fill bone defects of several fracture sites: specifically, proximal tibia [43,[79][80][81][82], distal tibia [82], distal radius [83,84] and calcaneus [82]. It provides adequate mechanical stability in open [43,81,82] and arthroscopic [80] management of tibia plateau fractures.…”

Section: Clinical Indicationsmentioning

confidence: 99%

Bone substitutes in the Netherlands – A systematic literature review

Stok¹,

Lieshout²,

El-Massoudi³

et al. 2011

Acta Biomaterialia

212

130

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Autologous bone grafting is currently considered as the gold standard to restore bone defects. However, clinical benefit is not guaranteed and there is an associated 8-39% complication rate. This has resulted in the development of alternative (synthetic) bone substitutes. The aim of this systematic literature review was to provide a comprehensive overview of literature data of bone substitutes registered in the Netherlands for use in trauma and orthopedic surgery. Brand names of selected products were used as search terms in three available databases: Embase, PubMed and Cochrane. Manuscripts written in English, German or Dutch that reported on structural, biological or biomechanical properties of the pure product or on its use in trauma and orthopedic surgery were included. The primary search resulted in 475 manuscripts from PubMed, 653 from Embase and 10 from Cochrane. Of these, 218 met the final inclusion criteria. Of each product, structural, biological and biomechanical characteristics as well as their clinical indications in trauma and orthopedic surgery are provided. All included products possess osteoconductive properties but differ in resorption time and biomechanical properties. They have been used for a wide range of clinical applications; however, the overall level of clinical evidence is low. The requirements of an optimal bone substitute are related to the size and location of the defect. Calcium phosphate grafts have been used for most trauma and orthopedic surgery procedures. Calcium sulphates were mainly used to restore bone defects after tumour resection surgery but offer minimal structural support. Bioactive glass remains a potential alternative; however, its use has only been studied to a limited extent.

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“…Hence HAp has gained extensive acceptance for bone implant applica-tions due to its excellent biocompatibility, bioactivity, non immunogenic, non inflammatory behaviour and osteoconductive nature [3][4][5]. Literature survey reveals that most of the research work carried out on HAp based materials is concentrated on understanding bioactive nature of HAp with the help of in-vivo and in-vitro bioactivity tests [6][7][8][9]. Besides this, HAp is widely used in other application areas, which are basically based on electrical behaviour of HAp, such as chemical sensor [10][11][12], ionexchanger [13][14][15][16], fuel cell [17].…”

Section: Introductionmentioning

confidence: 99%

Effect of incubation in simulated body fluid on dielectric and photoluminescence properties of nano-hydroxyapatite ceramic doped with strontium ions

Mahabole¹,

Bahir²,

Kalyankar³

et al. 2012

JBiSE

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This paper reports the dielectric and photoluminescence measurements of ossiointegrated strontium doped hydroxyapatite bioceramic. The study on <i>invitro</i> bioactivity of Sr-HAp is carried out by using modified simulated body fluid. Dielectric properties of these ossiointegrated samples are studied in the frequency range 10 Hz to 1 MHz at room temperature. Dielectric constant is found to be decreasing with increase in incubation period and frequency of applied ac field. Higher the period of incubation and applied ac frequency, higher is the dielectric loss. AC conductivity shows frequency independent behaviour for all samples in lower frequency region and then increases linearly with increase in frequency. Sample incubated for longer duration shows higher conductivity. The optical properties of incubated Sr-HAp samples are also investigated with photoluminescence (PL) technique. The PL study shows the blue emission at around 476 nm when excited at 409 nm. The PL in tensity increases with increase in incubation duration and Sr-substitution

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Osseous integration of bovine hydroxyapatite ceramic in metaphyseal bone defects of the distal radius

Cited by 38 publications

References 27 publications

Microvascular response to calcium phosphate bone substitutes: an intravital microscopy analysis

Microvascular response to calcium phosphate bone substitutes: an intravital microscopy analysis

Bone substitutes in the Netherlands – A systematic literature review

Effect of incubation in simulated body fluid on dielectric and photoluminescence properties of nano-hydroxyapatite ceramic doped with strontium ions

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