Osmolality dependence of erythrocyte sedimentation and aggregation in a strong magnetic field

Iino, Masaaki; Okuda, Y.

doi:10.1002/1521-186x(200101)22:1<46::aid-bem5>3.0.co;2-0

Cited by 10 publications

(6 citation statements)

References 13 publications

(27 reference statements)

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“…A previous study found that sedimentation and aggregation of erythrocytes increased when the erythrocytes were suspended in a plasma solution and exposed to a strong SMF with a magnetic induction of 6.3 T. However, this aggregative phenomenon disappeared when the cells were immersed in 20% hematocrit saline solution (Iino 1997, Iino andOkuda 2001). Th ese results provide evidence that the eff ect of an SMF on erythrocytes is strongly related to their surrounding solution.…”

Section: Discussionmentioning

confidence: 99%

Influence of a static magnetic field on the slow freezing of human erythrocytes

Lin

Chang

Lee

et al. 2012

International Journal of Radiation Biology

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Section: Discussionmentioning

confidence: 99%

Influence of a static magnetic field on the slow freezing of human erythrocytes

Lin

Chang

Lee

et al. 2012

International Journal of Radiation Biology

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“…ELF MFs, as well as heat shock, proved to increase microvescicle motility in astrocytes [82]. Both sedimentation and aggregation of erythrocytes were MF-dependent [83]. At the level of cell-cycle kinetics and at that of cell culture proliferation, there was an agreement regarding the MF-effect: variations of Friend erythroleukemia cell proliferation, following the addition or deprivation of MFs [84], were consistent either with alteration of the onset of S-phase established after a 50 Hz MF exposure of normal human fibroblasts [85] or with change of the growth and colony forming ability after exposure of budding yeast to 50 Hz MFs [86].…”

Section: Biotargets Of Middle Complexity Exhibited a Moderate Mf-stabmentioning

confidence: 78%

A Theoretical Overview of Bioresponse to Magnetic Fields on the Earth’s Surface

Volpe¹

2014

IJG

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This survey points to the mechanisms of bioresponse caused by magnetic fields (MFs), paying attention to their action not only on ions, molecules and macromolecules, but also on cells, tissues and organisms. The significance of findings concerning the MF-dependence of cell proliferation, necrosis or apoptosis was judged by comparing the results obtained in a solenoid, where an MF can be added to the geomagnetic field (GMF), with those obtained in a magnetically shielded room, where the MFs can be attenuated or null. This comparative criterion was particularly appropriate when the differences detectable between the data provided by experimental samples and the data provided by control samples were rather small, as observed in estimating the MF-influence on total DNA replication, RNA transcription and polypeptide translation. The MF-induced inhibition of apoptosis was considered as a risk potentially leading to accumulation of cancer cells. The analysis also surveyed the MF-dependence of the interactions between host animal cells and infecting bacteria. In relation to studies on the origin and adaptation of life on the Earth, theoretical insights paving the way to elucidating the MF-interactions with biostructures and biosystems of different orders of organization evaluated the possible involvement of the so-called "biological windows". Analogously to what is known for ionizing radiations, the efficiency of the applied MFs appeared to depend on the complexity of their biological targets.

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“…Erythrocytes thawed from the SMF-coupled freezing process used in this study exhibited no obvious cell aggregation (Figure 3). Previous studies showed that when erythrocytes were immersed in a normal saline solution with an Hct of 20%, the effect of an SMF on erythrocyte aggregation was slight, even when the cells were exposed to a strong SMF of up to 6.3 T [35], [36]. Additionally, ATP and 2,3-DPG metabolite tests were used to assess erythrocyte function after thawing [31].…”

Section: Discussionmentioning

confidence: 99%

Slow Freezing Coupled Static Magnetic Field Exposure Enhances Cryopreservative Efficiency—A Study on Human Erythrocytes

et al. 2013

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The aim of this study was to assess the cryoprotective effect of static magnetic fields (SMFs) on human erythrocytes during the slow cooling procedure. Human erythrocytes suspended in 20% glycerol were slowly frozen with a 0.4-T or 0.8-T SMF and then moved to a −80°C freezer for 24 hr. The changes in survival rate, morphology, and metabolites of the thawed erythrocytes were examined. To understand possible cryoprotective mechanisms of SMF, membrane fluidity and dehydration stability of SMF-exposed erythrocytes were tested. For each test, sham-exposed erythrocytes were used as controls. Our results showed that freezing coupled with 0.4-T or 0.8-T SMFs significantly increased the relative survival ratios of the frozen-thawed erythrocytes by 10% and 20% (p<0.001), respectively. The SMFs had no effect on erythrocyte morphology and metabolite levels. However, membrane fluidity of the samples exposed to 0.8-T SMF decreased significantly (p<0.05) in the hydrophobic regions. For the dehydration stability experiments, the samples exposed to 0.8-T SMF exhibited significantly lower (p<0.05) hemolysis. These results demonstrate that a 0.8-T SMF decreases membrane fluidity and enhances erythrocyte membrane stability to resist dehydration damage caused by slow cooling procedures.

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Osmolality dependence of erythrocyte sedimentation and aggregation in a strong magnetic field

Cited by 10 publications

References 13 publications

Influence of a static magnetic field on the slow freezing of human erythrocytes

Influence of a static magnetic field on the slow freezing of human erythrocytes

A Theoretical Overview of Bioresponse to Magnetic Fields on the Earth’s Surface

Slow Freezing Coupled Static Magnetic Field Exposure Enhances Cryopreservative Efficiency—A Study on Human Erythrocytes

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