Osmolality and oncotic pressure of volume expanding fluids for newborn administration

Effect of Resuscitative Fluids Upon Physical Properties of Blood Perfusing the Brain

“…Such solutions can be rapidly and accurately formulated using solutions readily available in most delivery rooms. 14…”

Hyperoncotic enhancement of fetal pulmonary growth after tracheal occlusion: an alveolar and capillary morphometric analysis

“…Nonetheless, we hypothesized that the positive oncotic pressure induced in the fetal lung liquid by delivery of concentrated albumin led to an active increase in lung liquid volume, which, in turn, maximized the lung growth response known to occur after TO. The 25% formulation of albumin used herein produces an oncotic pressure that is roughly 5 times greater than an equivalent volume of plasma, while maintaining isosmolarity [24,25]. When injected intravenously, for example, this formulation will draw approximately 3.5 times its volume of additional fluid into the circulation [24].…”