Orthostatic myoclonus: An underrecognized cause of unsteadiness?

Gasca-Salas, Carmen; Arcocha, Juan; Artieda, Julio; Pástor, Pau

doi:10.1016/j.parkreldis.2013.07.004

Cited by 22 publications

(16 citation statements)

References 12 publications

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“…in 3 PD patients, whose mycolonic frequency ranged between 9.5 and 15 Hz . Interestingly, OM has been subsequently found to be the most frequent cause of unsteadiness on standing among 93 elderly subjects studied (17.2%), followed by OT (13.9%) and psOT (12.9%) . It is our experience that OM frequency can exceed 15 Hz (Fig.…”

Section: Orthostatic Myoclonusmentioning

confidence: 73%

“…OM can present isolated from any identifiable neurological disease (and therefore is supposed to be idiopathic) or in association with a different number of neurological or systemic conditions, including atypical parkinsonism, Alzheimer's disease, mild cognitive impairment, normal pressure hydrocephalus, cerebral amyloid angiopathy, systemic necrotizing vasculitis, and chronic renal failure . As to the EMG characteristics, patients with idiopathic or symptomatic OM are indistinguishable.…”

Section: Orthostatic Myoclonusmentioning

confidence: 99%

“…The figure by Gasca‐Salas et al. suggests that OM is very likely underdiagnosed and further clinical series would be needed to assess its progression and response to treatment.…”

Section: Orthostatic Myoclonusmentioning

confidence: 99%

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Shaking on Standing: A Critical Review

Erro

Bhatia

Cordivari

2014

Movement Disord Clin Pract

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Orthostatic tremor is a rare condition, though its exact prevalence is unknown, which is clinically characterized by a feeling of unsteadiness or being about to fall on standing and which disappears on walking, sitting, or lying down. It is generally accepted that classic orthostatic tremor manifests with a highfrequency tremor (>13 Hz) of the legs when standing. However, a number of patients initially reported as orthostatic tremor did not actually have such electrophysiological features. It is our experience that there is a clinical spectrum of different conditions presenting as shaking on standing, and this highlights the importance of the electrophysiology to aid the differential diagnosis of these disorders. Here, we provide a critical review of the clinical spectrum of shaking on standing, along with demonstrative electrophysiological recordings of some of these conditions.

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Section: Orthostatic Myoclonusmentioning

confidence: 73%

Section: Orthostatic Myoclonusmentioning

confidence: 99%

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Shaking on Standing: A Critical Review

Erro

Bhatia

Cordivari

2014

Movement Disord Clin Pract

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“…The presence of enlarged cortical somatosensory evoked potentials (SEPs) or stimulus-sensitive myoclonus can support a cortical generator for myoclonus 12. Gasca Salas et al101 found enlarged SEPs in 20% of their OM patients and van Gerpen found none 15. Stimulus-sensitive myoclonus was also absent in OM patients 15.…”

Section: Resultsmentioning

confidence: 99%

Orthostatic Tremor and Orthostatic Myoclonus: Weight-bearing Hyperkinetic Disorders: A Systematic Review, New Insights, and Unresolved Questions

Hassan

Gerpen

2016

Tremor and Other Hyperkinetic Movements

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“…OT tends to rapidly diminish when the patient begins to walk, while the lower extremity shaking observed in OM patients typically persists, impacting the patient’s gait . OM is more frequently associated with concomitant with neurodegenerative disorders than OT (Gerschlager et al, 2004, Glass et al, 2007, Gasca-Salas et al, 2013, van Gerpen, 2014). Video 2Demonstration of orthostatic tremor with accompanying SEMG.…”

mentioning

confidence: 99%