Orthostatic hypoxaemia in dialysed adult polycystic kidney disease patients

Korzets, Ze’ev; Golan, Eliezer; Ben-Chitrit, S.; Smorjik, Y; Os, Polianskaia; Bernheim, J

doi:10.1093/ndt/12.4.733

Cited by 5 publications

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“…The authors, to account for this phenomenon, advanced the hypothesis of the existence of intrapulmonary shunting associated with intrapulmonary vascular dilatation. This is the same mechanism called to explain severe hypoxemia in chronic liver diseases [ 9 ]. However, in this case it is not possible to exclude a right-to-left interatrial shunt through a misdiagnosed patent foramen ovale.…”

Section: Discussionmentioning

confidence: 94%

An Unusual Cardiac Manifestation in Autosomal Dominant Polycystic Kidney Disease

Catapano

Pancaldi

Napoleone

et al. 2012

Case Reports in Nephrology

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Autosomal dominant polycystic kidney disease is a common hereditary disorder characterized by renal and extrarenal, cystic and noncystic manifestations. Connective tissue defects, including cerebral aneurysm, meningeal diverticula, abdominal wall hernias, intestinal diverticula, and cardiac valvular abnormalities, are widely known manifestations. Instead intracardiac aneurysms have never been reported in adults with autosomal dominant polycystic kidney disease. We describe a 65-year-old patient with end-stage renal disease due to autosomal dominant polycystic kidney disease and an atrial septum aneurysm associated with platypnoea-orthodeoxia syndrome.

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Section: Discussionmentioning

confidence: 94%

An Unusual Cardiac Manifestation in Autosomal Dominant Polycystic Kidney Disease

Catapano

Pancaldi

Napoleone

et al. 2012

Case Reports in Nephrology

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show abstract

“…We have, re cently. documented the occurrence of an orthostatic de cline in p02 in dialyzed adult polycystic kidney disease patients [13]. The existence of a shunt provides the best plausible explanation for this unique phenomenon.…”

Section: Discussionmentioning

confidence: 96%

Nonocclusive Mesenteric Infarction in Continuous Ambulatory Peritoneal Dialysis

Korzets¹,

Ben-Chitrit²,

Bernheim³

1996

Nephron

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Nonocclusive mesenteric infarction has recently been diagnosed with increasing frequency in dialysis patients. Although most reports have concerned patients on hemodialysis, the condition has also been reported to occur in patients on continuous ambulatory peritoneal dialysis. This report describes such a case developing in a woman whose end-stage renal failure was due to adult polycystic kidney disease. Associated predisposing factors were the presence of orthostatic hypoxemia, postural hypotension and extensive atheromatous changes of the abdominal aorta. In keeping with the known difficulty of establishing the diagnosis of mesenteric ischemia, the diagnosis in our patient was also delayed. She was initially thought to suffer from an episode of peritonitis and/or colonic perforation secondary to the performance of a cleansing enema. Only upon showing pneumatosis coli of the right colon on abdominal computerized tomography was the correct diagnosis made. Laparotomy revealed extensive necrosis of the ascending and transverse colon. A total colectomy and ileorectal anastomosis were performed. The patient died on the 17th day following surgery. This case serves to illustrate that mesenteric infarction should be considered in predisposed patients on continuous ambulatory peritoneal dialysis. The presence of peritonitis may mask the underlying pathology and waylay the unwary physician.

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Noninfectious Complications of Peritoneal Dialysis

Bargman¹

2009

Nolph and Gokal’s Textbook of Peritoneal Dialysis

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Orthostatic hypoxaemia in dialysed adult polycystic kidney disease patients

Abstract: Orthostatic hypoxaemia may occur in dialysed patients whose ESRF is due to APKD.

Cited by 5 publications

References 0 publications

An Unusual Cardiac Manifestation in Autosomal Dominant Polycystic Kidney Disease

An Unusual Cardiac Manifestation in Autosomal Dominant Polycystic Kidney Disease

Nonocclusive Mesenteric Infarction in Continuous Ambulatory Peritoneal Dialysis

Noninfectious Complications of Peritoneal Dialysis

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