“…Orthostatic hypotension (OH), defined as a blood pressure (BP) drop of at least 20 mm Hg systolic and/or >10 mm Hg diastolic after postural change (Freeman et al, 2011), is highly prevalent in older adults (Cooke et al, 2013;Frewen et al, 2014;Timmermans et al, 2018), whereas the effectiveness of non-pharmacological interventions are limited (De Bruïne et al, 2017). OH may be accompanied by clinical symptoms, e.g., lightheadedness and dizziness (Juraschek et al, 2017(Juraschek et al, , 2018, and is associated with poor clinical outcome such as impaired physical performance (Pasma et al, 2014;de Bruïne et al, 2018;Mol et al, 2018b), falls (Saedon et al, 2016;Mol et al, 2018a), cognition (Iseli et al, 2019), cardiovascular diseases (Verwoert et al, 2008;Ricci et al, 2015) and mortality (Verwoert et al, 2008;Lagro et al, 2012;Rockwood et al, 2012;Ricci et al, 2015;Frith et al, 2016). Sensitivity for the diagnosis of OH is higher for continuous BP measurement than for intermittent BP measurements after standing up, and continuous BP measurement has shown to be stronger associated with physical performance (Pasma et al, 2014;de Bruïne et al, 2018).…”