2016
DOI: 10.1016/j.clinph.2015.12.017
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Orthostatic hypertension: An underestimated cause of orthostatic intolerance

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Cited by 30 publications
(27 citation statements)
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“…In addition to OH or POTS, we assured the presence of orthostatic hypertension during HUT in patients with orthostatic symptoms. We have previously reported that orthostatic intolerance due to orthostatic hypertension has been underestimated 19 . The prevalence of orthostatic hypertension in the present study was 3.2% and only 20% of them were symptomatic.…”
Section: Discussionmentioning
confidence: 99%
“…In addition to OH or POTS, we assured the presence of orthostatic hypertension during HUT in patients with orthostatic symptoms. We have previously reported that orthostatic intolerance due to orthostatic hypertension has been underestimated 19 . The prevalence of orthostatic hypertension in the present study was 3.2% and only 20% of them were symptomatic.…”
Section: Discussionmentioning
confidence: 99%
“…Early pathogenetic studies [ 35 ] on orthostatic hypertension showed that in patients with this condition, excessive gravitational pooling of blood in the lower extremities causes a reduction of cardiac output, which leads to a compensatory sympathetic hyperactivity followed by an abnormally intense arterial vasoconstriction which raises the diastolic blood pressure. Increased peripheral vascular resistance has been demonstrated in patients with orthostatic hypertension who underwent a head-up tilt test [ 36 ]. Further support of a role for peripheral resistance in the pathogenesis of this condition comes from a case report in which a patient with severe symptomatic orthostatic hypertension was successfully treated with an alpha blocker [ 37 ].…”
Section: Discussionmentioning
confidence: 99%
“…The recurrent symptoms of OHT greatly impact on the academic performance and daily life in children and adolescents (11). Moreover, previous studies showed that OHT in young adults was associated with elevated risk of suffering from essential hypertension in the future (5,14), which also drew focus on adolescents and children with OHT. However, up to now, the mechanism for pediatric OHT is poorly understood (13,15,16).…”
Section: Introductionmentioning
confidence: 99%