Orthostasis, the Autonomic Nervous System, and Abdominal Pain in Children: Is There a Relation Between Postural Orthostatic Tachycardia and Recurrent Abdominal Pain?

Alexander, Mark E.

doi:10.1097/01.mpg.0000338964.62926.28

Cited by 1 publication

(2 citation statements)

References 26 publications

(17 reference statements)

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“…Gastrointestinal (GI) symptoms occur commonly in patients with POTS and are a source of considerable frustration, disability, and impairment in quality of life . The cause of these GI symptoms, in many instances, remains unclear.…”

Section: Introductionmentioning

confidence: 99%

“…3 Gastrointestinal (GI) symptoms occur commonly in patients with POTS and are a source of considerable frustration, disability, and impairment in quality of life. [6][7][8][9][10] The cause of these GI symptoms, in many instances, remains unclear. Studies evaluating gastric transit in POTS have shown that a significant proportion of patients with POTS have abnormalities in gastric emptying, with rapid emptying occurring more commonly than delayed emptying.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Factors Associated With Use of Nonoral Nutrition and Hydration Support in Adult Patients With Postural Tachycardia Syndrome

Tseng

Traub

Harris

et al. 2018

J Parenter Enteral Nutr

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Background Patients with postural tachycardia syndrome (POTS) often have gastrointestinal (GI) symptoms. Occasionally, these symptoms can be so severe that nonoral nutrition/hydration support (NONHS), including intravenous fluids (IVFs), enteral nutrition (EN), and parenteral nutrition (PN), becomes necessary. Methods This is a retrospective cohort study of adult patients diagnosed with POTS at the Mayo Clinic Arizona from January 2010 to January 2017 with a minimum of 6 months of follow up. Demographic information, symptomatology, medications, GI testing, autonomic and autoantibody testing, and healthcare utilization data were abstracted from the electronic medical record. Results Three‐hundred thirty‐two patients with POTS were included, of which 32 required NONHS. Patients receiving NONHS were more likely to be female; have lower body mass index; have GI symptoms including nausea, vomiting, diarrhea, and constipation; have abdominal pain; use opiates; have delayed gastric emptying; see more specialists; and be seen in an emergency room or be hospitalized for symptoms. Of these patients, 21 (66%) required IVF, 19 (59%) required EN, and 9 (28%) required PN. Six (19%) patients required all 3 NONHS modalities at some point during their follow‐up period. Conclusions NONHS may be required in a subset of patients with POTS. Those receiving NONHS have more severe symptoms and abnormal GI motility and autonomic testing and exhibit greater healthcare utilization. Management of these patients is complex and challenging and requires a multidisciplinary approach. Further prospective studies are needed to identify optimal management strategies.

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Section: Introductionmentioning

confidence: 99%