Orthopaedic applications of injectable biomaterials

McLaren, A. C.; Estes, Chris S.

doi:10.1533/9780857091376.2.202

Cited by 4 publications

(2 citation statements)

References 112 publications

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“…9 Calcium phosphate has great compressive strength of up to 4 to 10 times greater than cancellous bone, which may allow for immediate construct stability and early postoperative weight bearing. 9 Both traditional and fast-setting BGS have traditionally been used in the setting of fracture repair, including tibial plateau repair, to avoid the risk of donor-site morbidity that is often associated with autograft. 10 Fast-setting BGS now have been used in fracture repair for over 20 years.…”

Section: Discussionmentioning

confidence: 99%

“…There have been several techniques described to successfully achieve single-stage ACLR including: stacked screws, corticocancellous allograft "match sticks," and cylin-drical allograft bone dowels. 3,[6][7][8][9] One such more recent approach has been described by Werner et al, where the authors detail the use of a cannulated structural allograft bone dowelsometimes multiple, stacked dowels-to address bony defects in a single-stage revision. 4 This is an excellent technique but may be technically challenging at times.…”

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confidence: 99%

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Clinical Outcomes of Single-Stage Revision Anterior Cruciate Ligament Reconstruction Using a Fast-Setting Bone Graft Substitute

Rogers,

Adsit,

Serbin

et al. 2023

J Knee Surg

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Revision anterior cruciate ligament reconstruction (ACLR) can be achieved in a single-stage or two-stage approach. Single-stage revisions have several advantages, including one less operation, decreased cost, and a quicker recovery for patients. Revision ACLR can be complicated by malpositioned or dilated bone tunnels, which makes a single-stage revision more challenging or sometimes necessitates a two-stage approach. The use of fast-setting bone graft substitutes (BGS) has been described in recent literature as a strategy to potentially help address this problem in the setting of single-stage revision ACLR. The aim of this study was to evaluate patient-reported clinical outcomes of patients who have undergone single-stage revision ACLR using fast-setting BGS to address prior malpositioned or dilated tunnels. A retrospective review was conducted of the first nine consecutive patients who had undergone single-stage revision ACLR using a fast-setting BGS by a single surgeon between May 2017 and February 2020 with a minimum of 2-year follow-up. Patient-reported clinical outcomes, including the International Knee Documentation Committee (IKDC) questionnaire, the Tegner Lysholm Knee Scoring Scale, patient satisfaction questions, and the need for additional surgery were evaluated for this group between 26 and 49 months postoperative. Of the nine patients eligible for inclusion, eight patients (88.9%) were evaluated, and one was lost to follow-up. At an average follow-up of 37.9 months (range: 27.8–55.7), the mean postoperative IKDC score was 75.0 ± 11.3, and the mean postoperative Tegner Lysholm Knee Score was 83.0 ± 17.6. None of the patients required additional revision surgery or experienced construct failure at the time of follow-up. Seven of eight respondents (87.5%) had their preoperative expectations met with the surgery, and 100% of patients stated they would have the surgery again. Single-stage revision ACLR using fast-setting BGS showed overall positive clinical outcomes for this pilot group of patients at a minimum 2-year follow-up. In select revision scenarios, these materials may be a valuable option to allow the filling of defects without compromising fixation or clinical outcomes.

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Section: Discussionmentioning

confidence: 99%