“…LSCI has been applied successfully to evaluate microcirculation in Microvascular Research 97 (2015) [137][138][139][140][141][142][143][144][145][146] Abbreviations: aPTT,activated partial thromboplastin time; CLP,cecal ligation and puncture; EPCR, endothelial PC receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HR, heartrates; ICAM-1, intercellular adhesion molecule; i.p., injectedintraperitoneally;LPS, lipopolysaccharide; LSCI, laser speckle contrast imaging; MAP, mean arterial pressure; MPO, myeloperoxidase; PAI-1, plasminogen activator inhibitor-1; PT, prothrombin time; ROI, region of interest; RT-PCR, reverse transcription-PCR; RT-PCR, reverse transcription-PCR; TF, tissue factor; TM, thrombomodulin; TUNEL, terminal deoxyribonucleotidyltransferasemediated dUTP nick-end labeling; VCAM-1, vascular cell adhesion molecule. the skin, gastrointestinal mucosa, and brain cortex (Senarathna et al, 2013, (Schiessler et al, 2002, (Briers et al, 2013. LSCI has been used to monitor liver microcirculation during temporary occlusion of blood inflow (Sturesson et al, 2013a(Sturesson et al, , 2013b.…”