Orthodontic and orthognathic management of a patient with osteogenesis imperfecta and dentinogenesis imperfecta: a case report

Abstract

This case report describes a patient's severe Class III malocclusion, managed with a combination of orthodontic and orthognathic treatment. The medical history was complicated by osteogenesis imperfecta and dentinogenesis imperfecta. In addition the patient was a Jehovah's Witness. Patients with osteogenesis imperfecta carry an increased risk of perioperative haemorrhage, and this led to bimaxillary surgery being carried out as two discrete surgical episodes for the patient described. In addition, the risk of enamel fracture led to orthodontic bands being cemented on all teeth. In spite of the increased risks a successful outcome was achieved.

Orthognathic bimaxillary surgery in two patients with osteogenesis imperfecta and a review of the literature

“…KINDELAN et al reported a case with severe class II malocclusion, osteogenesis imperfecta and dentinogenesis imperfecta 13 . The patient was a Jehovah's Witness and could not accept blood trans- There are also risks of metabolic defects, for example OI patients experience a greater incidence of hyperthermia with general anaesthesia, which can develop into malignant hyperthermia 25 .…”

Combined Treatment with Laser Sintering and Zirconium: A Case Report of Dentinogenesis Imperfecta

“…Osteogenesis imperfecta (OI), also known as “brittle bone”, disease is a genetically determined connective tissue disorder that results from mutations of 2 genes (COL1A1 and COL1A2) responsible for the formation of type 1 collagen [1–3]. …”

“…Radiographically, teeth affected by DI show cervical constriction, bulbous crowns, short roots, short pulp chambers, and obliterated canals [10]. Adult patients with OI frequently exhibit class III malocclusions, anterior or posterior cross-bite, posterior open-bite, and vertical height loss [1, 3, 11]. …”

Dentofacial rehabilitation by osteodistraction, augmentation and implantation despite osteogenesis imperfecta

“…Because osteogenesis imperfecta is frequently associated with dentinogenesis imperfecta, deformity, impaction and agenesis of teeth can also be observed in patients suffering from this disorder 5 . Despite these functional and aesthetic problems, dental implant rehabilitation, bone graft augmentation and orthognathic surgery are extremely rare in these patients 2,4 . In particular, the treatment of a severe atrophic maxilla in osteogenesis imperfecta is challenging.…”