Orthobiologics in knee osteoarthritis, dream or reality?
Nicolaas Cyrillus Budhiparama,
Dananjaya Putramega,
Imelda Lumban-Gaol
Abstract:Cartilage restoration or repair, also known as orthobiologic therapy, is indicated after the failure of conservative or supportive treatment. However, there is paucity in evidence supporting the efficacy of orthobiologic therapy. The blood-derived products, such as platelet-rich plasma (PRP), is one of the commonly used orthobiologic therapy for knee osteoarthritis. Several studies have shown that PRP is superior to other treatments, but the anatomic changes are scarce. Treatment with mesenchymal stem cells (M… Show more
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