ortho-Heterobimetallic Arylene Complex: A New Platform for Regioselective Difunctionalization

Abstract

Regioselective ortho difunctionalization of arenes is highly desirable yet challenging in organic synthesis. Here, we briefly discuss various methods for ortho difunctionalization of arenes, and highlight a novel ortho heterobimetallic arylene complex enabled by heterobimetallic synergism, which shows great potential in regioselective ortho difunctionalizations.