Oropharyngeal pH Monitoring for the Detection of Liquid and Aerosolized Supraesophageal Gastric Reflux

Wiener, Gregory; Tsukashima, Ross; Kelly, Colleen; Wolf, E. H.; Schmeltzer, M.; Bankert, Charles; Fisk, Lauren; Vaezi, Michael F.

doi:10.1016/j.jvoice.2007.12.005

Cited by 118 publications

(124 citation statements)

References 16 publications

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“…Благодаря этому исследованию возможно выявить связь рефлюкса с симптомами болезни и диагностировать любой тип рефлюкса (кислый, слабокислый, слабощелочной, жидкостный или газовый), его значение особо велико у пациен-тов с внепищеводными формами гастроэзофагеаль-ного рефлюкса, поскольку жалобы может вызывать любой тип рефлюкса [18]. Так, с помощью данного метода была показана потенциальная роль слабо-кислых газовых рефлюксов, выводящих избыток за-глатываемого при еде воздуха (отрыжка), в развитии фарингита и ларингита при гастроэзофагеальной рефлюксной болезньи [19]. Эти наблюдения согласу-ются с отечественными данными о преимущественно эндоскопически-негативных формах болезни у паци-ентов с хроническим фарингитом, ассоциированным гастроэзофагеальной рефлюксной болезнью и клас-сическим рефлюкс-синдромом [20].…”

Section: оригинальные статьи в помощь практическому врачуunclassified

Extraoesophageal Manifestations of Gastroesophageal Reflux Disease in the Practice of Pediatric Otorhinolaryngologist

Асманов¹,

Ханакаева²,

Пивнева³

2017

Ross. vestn. perinatol. pediatr.

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Section: оригинальные статьи в помощь практическому врачуunclassified

Extraoesophageal Manifestations of Gastroesophageal Reflux Disease in the Practice of Pediatric Otorhinolaryngologist

Асманов¹,

Ханакаева²,

Пивнева³

2017

Ross. vestn. perinatol. pediatr.

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“…The Dx-pH measurement system, called Restech (Respiratory Technology Corp., San Diego, CA, United States), was designed to detect aerosolized acid, thus identifying patients whose symptoms are due to acidic mist or liquid refluxing into the pharynx. Because the distal part containing the pH sensor does not traverse the UES, it is more comfortable than a conventional pH catheter, and it does not require esophageal manometry [17] . Restech has a higher frequency of measurement than older catheter-based pH probes and wireless pH probes, with a pH measurement obtained every 0.5 s (sampling rate, 2 Hz), compared with traditional catheter-based pH probes, which sample every 4 s to 5 s (at a rate of 0.2-0.25 Hz), and wireless pH probes, with a pH measurement every 6 s (0.17 Hz).…”

Section: Dx-ph (Restech)mentioning

confidence: 99%

“…In this context, the advent of novel esophageal function testing, such as impedance-pH monitoring (MII-pH) and high resolution manometry (HRM), has allowed for relevant progress in the understanding of the pathophysiological mechanisms contributing to the development of GERD and, thereafter, its diagnosis and management. Moreover, the role of new technology to detect laryngopharyngeal reflux (LPR) [16][17][18] , as well as the presence of pepsin in clinical samples [19] , deserves careful consideration. The aim of the present review article is to report on the current literature about recent advances in diagnosing GERD.…”

Section: Introductionmentioning

confidence: 99%

Esophageal testing: What we have so far

Bortoli¹,

Martinucci²,

Bertani³

et al. 2016

WJGP

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Gastroesophageal reflux disease (GERD) is a common disorder of the gastrointestinal tract. In the last few decades, new technologies have evolved and have been applied to the functional study of the esophagus, allowing for the improvement of our knowledge of the pathophysiology of GERD. High-resolution manometry (HRM) permits greater understanding of the function of the esophagogastric junction and the risks associated with hiatal hernia. Moreover, HRM has been found to be more reproducible and sensitive than conventional water-perfused manometry to detect the presence of transient lower esophageal sphincter relaxation. Esophageal 24-h pH-metry with or without combined impedance is usually performed in patients with negative endoscopy and reflux symptoms who have a poor response to anti-reflux medical therapy to assess esophageal acid exposure and symptom-reflux correlations. In particular, esophageal 24-h impedance and pH monitoring can detect acid and non-acid reflux events. EndoFLIP is a recent technique poorly applied in clinical practice, although it provides a large amount of information about the esophagogastric junction. In the coming years, laryngopharyngeal symptoms could be evaluated with up and coming non-invasive or minimally invasive techniques, such as pepsin detection in saliva or pharyngeal pH-metry.

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“…To obtain our intraoperative pH measures, the Restech® Dx-pH test (Respiratory Technology Corp., San Diego, CA, USA) was selected for this purpose as it was developed to measure reflux in patients suspected of having extraesophageal symptoms presumably related to GERD [4,5]. While traditional hypopharyngeal pH catheters are prone to drying-out effects, which may cause misleading results due to pseudoreflux, the Restech probe reportedly resists drying, and does not require contact with fluid or tissue for electrical continuity.…”

Section: Interventionmentioning

confidence: 99%

Documenting the Hypopharyngeal Environment of Patients Undergoing General Endotracheal Tube Anesthesia: A First Look at Intraoperative pH Characteristics

Regenbogen¹

2015

Otolaryngol (Sunnyvale)

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OtolaryngologyOto la ry n g ol ogy: Op en A c ce ss ISSN: 2161-119XRegenbogen et al., Otolaryngology 2015, 5 AbstractObjectives: While laryngeal injuries are important and not infrequent following both short and extended endotracheal tube exposure, little detailed information is available regarding the hypopharyngeal environment during intubation. The objective of this pilot study was to explore a simple method of accurately documenting hypopharyngeal pH values in surgical patients undergoing endotracheal tube anesthesia and to report the findings.Methods: Twenty volunteers were continuously monitored intra-operatively using a commercially available hypopharyngeal pH monitoring system. Demographics, pre-and postoperative voice and reflux self reported survey data were also collected. Results:No complications associated with the pH monitoring system occurred. Median pH was 6.5 (range 6.0-7.0); median recorded time in minutes was 183.9 (range 130.7 -323.5). 13/20 patients had pH>5.0 ≤ 5.5 events, for up to 113 minutes of monitored time; 2/20 patients had pH>4.0 ≤ 5.0 events, for up to 8 minutes of monitored time; 2/20 patients had pH ≤ 4.0 events, for up to 61 minutes of monitored time. Conclusions:The hypopharyngeal pH test was used successfully to intra-operatively record hypopharyngeal pH variations. Extended pharyngeal exposures to low pH environments were commonly documented. No associations were found with patient survey scores. Future research appears warranted to expand this study, identify "at-risk" populations and to rigorously evaluate an expanded set of voice-related and lower airway clinical outcomes measures.

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Oropharyngeal pH Monitoring for the Detection of Liquid and Aerosolized Supraesophageal Gastric Reflux

Cited by 118 publications

References 16 publications

Extraoesophageal Manifestations of Gastroesophageal Reflux Disease in the Practice of Pediatric Otorhinolaryngologist

Extraoesophageal Manifestations of Gastroesophageal Reflux Disease in the Practice of Pediatric Otorhinolaryngologist

Esophageal testing: What we have so far

Documenting the Hypopharyngeal Environment of Patients Undergoing General Endotracheal Tube Anesthesia: A First Look at Intraoperative pH Characteristics

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