Oropharyngeal Candidiasis as a Presenting Symptom of Crohn’s Disease

Sharif, Muhammad; Saddique, Muhammad; Zahid, Muhammad; Khan, Dawlat; Bashir, Tabinda; Murshed, Khaled

doi:10.1159/000506931

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…Another study found that 31% UC patients had a history of smoking, while 16% were current smokers (ILTAR et al, 2020). Our study's total number of surgeries in CD patients was comparable to the previous study (Sharif et al, 2020). Despite the lingering duration between the onset of symptoms and disease diagnosis compared to other studies, there was a marked difference in the need for surgical intervention.…”

Section: Discussionsupporting

confidence: 77%

Clinical Features of Crohn's Disease and Ulcerative Colitis

MALIK,

SHAHID,

MALIK

2023

Biol Clin Sci Res J

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The retrospective study was conducted in the Department of Gastroenterology, THQ Hospital, from March 2020 to March 2021 to assess CD and UC's clinical characteristics and demographic features in a relatively diverse group of patients. The study included patients diagnosed with IBD. The questionnaire was used to gather data regarding clinical and demographic features, disease duration, and family history of IBD, surgical interventions, extra-intestinal manifestations, and clinical and socio-economic variables relevant to CD and UC patients. 500 patients were included in the study, of which 135 (28%) had CD and 365 (73%) had UC. UC patients predominantly had bloody diarrhea and/or hematochezia, while CD patients had abdominal pain. 50% of CD patients required surgical intervention, compared to only 9.8% of UC patients. Evaluation of chemotherapy showed that 66.6% of CD patients and 37.8% of UC patients received steroid therapy. 22 (6%) UC patients and 7 (5.1%) CD patients had a family history of IBD (P=.819). The most frequent extra-intestinal complication in UC patients was PSC; it was acute arthropathy in CD patients. It is concluded that the peak age of disease onset in UC and CD patients is similar to other Asian countries. There was non-significant male predominance for UC and CD. Diagnosis of CD is delayed compared to UC, which may be due to negligence towards disease symptoms.

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Section: Discussionsupporting

confidence: 77%

Clinical Features of Crohn's Disease and Ulcerative Colitis

MALIK,

SHAHID,

MALIK

2023

Biol Clin Sci Res J

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“…According to another review, Candida stands out among all GI fungal infections among IBD patients[ 14 ]. The authors of a similar case in which weight loss was also reported noted that fungal infections are observed more frequently among patients with CD than among those with UC[ 15 ]. Therefore, examinations for any signs of fungal infection should be performed routinely for these people.…”

Section: Discussionmentioning

confidence: 99%

Crohn’s disease in human immunodeficiency virus-infected patient: A case report

Vinikaite,

Kurlinkus,

Jasinskaite

et al. 2023

World J Clin Cases

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BACKGROUND Inflammatory bowel disease (IBD) is an autoimmune condition treated with immunosuppressive drugs. However, the need for immune system suppression becomes questionable when infection with the human immunodeficiency virus (HIV) occurs simultaneously and impacts the course of IBD. Our reported case represents the clinical course, prescribed treatment and its effect, as well as clinical challenges faced by physicians in a combination of such diseases. We also present a comprehensive literature review of similar cases. CASE SUMMARY A 49-year-old woman suffering from a newly diagnosed Crohn’s disease was hospitalized due to exacerbated symptoms (abdominal pain, fever, and weight loss). During her hospital stay, she tested positive for HIV. With conservative treatment, the patient improved and was discharged. In the outpatient clinic, her HIV infection was confirmed as stage C3, and antiretroviral treatment was initiated immediately. That notwithstanding, soon the patient was rehospitalized with pulmonary embolism and developed a series of complications because of the subsequent coexistence of IBD and HIV. After intensive and meticulous treatment, the patient’s condition has improved and she remains in remission. CONCLUSION The paucity of studies and data on the coexistence of HIV and IBD leaves clinicians doubting the optimal treatment options.

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Oropharyngeal Candidiasis as a Presenting Symptom of Crohn’s Disease

Cited by 2 publications

References 12 publications

Clinical Features of Crohn's Disease and Ulcerative Colitis

Clinical Features of Crohn's Disease and Ulcerative Colitis

Crohn’s disease in human immunodeficiency virus-infected patient: A case report

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