Orofacial cleft malformations: Associations with maternal and infant characteristics in Washington State

DeRoo, Lisa A.; Gaudino, James A.; Edmonds, Larry D.

doi:10.1002/bdra.10114

Cited by 54 publications

(52 citation statements)

References 32 publications

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“…However, larger studies failed to identify advanced maternal age as a risk factor for OCs [31,32]. Conversely, other studies found a greater risk for CL among younger mothers [33,34]. Infant sex influences the risk for OCs.…”

Section: Discussionmentioning

confidence: 99%

Incidence of Orofacial Clefts in Kumasi, Ghana

Agbenorku

Yore

Danso

et al. 2013

ISRN Plastic Surgery

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Background. Cleft lip and cleft palate are among the most common orofacial congenital anomalies. This study is to establish Orofacial Clefts Database for Kumasi, Ghana, with a view to extend it to other cities in future to obtain a national orofacial anomaly database. Methods. A descriptive prospective survey was carried out at eleven selected health facilities in Kumasi. Results. The total number of live births recorded was 27,449. Orofacial anomalies recorded were 36, giving an incidence of 1.31/1000 live births or 1 in 763 live births. The mean maternal age of cleft lip/palate babies was 29.85 years (range 18–40 years). The male : female ratio for the orofacial anomalies babies was 1.3 : 1; the male : female ratio was 0.5 : 1 in the cleft lip group, 1.3 : 1 in the cleft lip and palate group, and 4 : 1 in the cleft palate group. The majority of clefts were unilateral (69.4%, n=25), with females (n=14) outnumbering males (n=11). A family history of cleft was recorded with five babies (13.9%). Associated congenital anomalies were recorded in seven (19.4%) cleft lips and/or palates. Conclusion. The incidence of 1 in 763 live births found in this study indicates that cleft lip/palate is a common congenital anomaly in Kumasi.

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Section: Discussionmentioning

confidence: 99%

Incidence of Orofacial Clefts in Kumasi, Ghana

Agbenorku

Yore

Danso

et al. 2013

ISRN Plastic Surgery

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“…CHARS data have been used in many different epidemiologic studies to evaluate a range of birth defects. [17][18][19][20] Women were eligible for this study if they gave birth to two singleton infants between 1998 and 2008. Women whose first or second birth involved a multiple birth were excluded.…”

Section: Methodsmentioning

confidence: 99%

Relationship between interpregnancy interval and birth defects in Washington State

et al. 2011

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Objective: Interpregnancy interval (IPI) influences numerous adverse perinatal outcomes. IPI's impact on birth defects is unclear. Study Design:We conducted a population-based case-control study, using 1998 to 2008 administrative data from Washington State. A total of 10 772 cases, women whose second of two births resulted in an infant with a birth defect, were compared with 32 310 controls, women whose second of two births did not result in an infant with a birth defect.Result: Compared with mothers with an IPI between 18 to 23 months, those with an IPI <6 months or X60 months had elevated risks of delivering an infant with a birth defect (odds ratio ¼ 1.15, 95% confidence interval: 1.03 to 1.28, and odds ratio ¼ 1.15, 95% confidence interval: 1.04 to 1.26, respectively). Conclusion:We observed a J-shaped relationship between IPI and risk of having an infant with a birth defect. As this is one of the first studies to evaluate this association, confirmatory studies are needed.

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“…Compared to that review, this one has included 20 additional studies 6,7,8,9,10,11,12,13,14,24,43,79,83,95,99,102,103,122,125,188 that have added about 10,000 cases of defects, and 800,000 of controls. Another difference between the two reviews is that 19 studies about abdominal wall defects were included in the meta-analysis of the gastro-intestinal system in the previous review, whereas these defects were classified as pertaining to the musculoskeletal system in this review.…”

Section: Discussionmentioning

confidence: 99%

“…While this investigation was being carried out, a systematic review with 101 observational studies was published, and showed an association between maternal smoking during pregnancy and different birth defects in children 5 . This review, however, did not include a considerable number of relevant studies 6,7,8,9,10,11,12,13,14 . Moreover, defects of the abdominal wall, such as congenital diaphragmatic and inguinal hernia, gastroschisis, and omphalocele, which should be considered musculoskeletal abnormalities, according to the 10 th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) 15 were classified as gastrointestinal defects.…”

Section: Introductionmentioning

confidence: 99%

Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis

et al. 2014

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Orofacial cleft malformations: Associations with maternal and infant characteristics in Washington State

Abstract: The prevalences of orofacial clefts in Washington State in 1987-90 were similar to those of other states. This study is among the first to report a greater relative risk for isolated CL +/- CP among the infants of mothers < 20 years compared to older mothers.

Cited by 54 publications

References 32 publications

Incidence of Orofacial Clefts in Kumasi, Ghana

Incidence of Orofacial Clefts in Kumasi, Ghana

Relationship between interpregnancy interval and birth defects in Washington State

Maternal smoking during pregnancy and birth defects in children: a systematic review with meta-analysis

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