Orofacial antinociceptive effect and antioxidant properties of the hydroethanol extract of Hyptis fruticosa salmz ex Benth

Lima, Amanda C.B. de; Paixão, Mônica Silveira; Melo, Mônica Santos de Souza; Santana, Marília T.; Damascena, Nicole Prata; Dias, Antônio Santos; Porto, Yasmin C.B.S.; Fernandes, Ximene A.; Santos, Carlos César Ribeiro; Lima, Clésio Andrade; Quintans‐Júnior, Lucindo José; Estevam, Charles dos Santos; Araujo, Brancilene Santos de

doi:10.1016/j.jep.2012.12.031

Cited by 27 publications

(7 citation statements)

References 28 publications

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“…is an aromatic plant of the family Lamiaceae, endemic to Brazil, known as "alecrim-de-vaqueiro". Besides being popularly used as an anti-inflammatory plant using the infusion of its leaves, the antitumor properties of E. fruticosa were identified by alcoholic extracts of the leaves (de Lima et al, 2013). Furthermore, the essential oil of this species has antinociceptive properties and induces arterial hypotensive effect (Menezes et al, 2007;Santos et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Research Article Assessment of genetic diversity of a native population of Eplingiella fruticosa: a plant with therapeutic potential.

et al. 2017

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ABSTRACT. Eplingiella fruticosa (Salzm. ex Benth.) Harley & J.F.B. Pastore, ex Hyptis fruticosa Salzm. ex Benth. is an aromatic and medicinal plant of the family Lamiaceae, found mainly in regions with intense anthropic activity. Information on the genetic diversity of this species is scarce. However, it can be assessed using molecular markers that identify the level of diversity among phenotypically identical individuals. The present study aimed to characterize the genetic diversity of a native population of E. fruticosa from the State of Sergipe using ISSR molecular markers. Samples of 100 plants were collected in 11 municipalities of the State of Sergipe and analyzed using eight ISSR primers, resulting in 72 informative bands. The cluster analysis obtained using the neighbor joining method resulted in three groups: Group I consisted of 50 plants, mainly from the municipalities of Areia Branca, Estância, Japaratuba, Moita Bonita, Pirambu, and Salgado; Group II was .250), and the greatest distance occurred between plants EPF50 and EPF96 (0.9778). The Shannon index had a mean value of 0.42, and diversity was considered moderate. Heterozygosity had a mean value of 0.267 and was considered low. Polymorphic information content (0.253) was considered moderately informative. Genetic diversity of E. fruticosa plants was intermediate, and the results of the present study can assist in the conservation and use of the genetic resources of this species.

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Section: Introductionmentioning

confidence: 99%

Research Article Assessment of genetic diversity of a native population of Eplingiella fruticosa: a plant with therapeutic potential.

et al. 2017

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“…This aromatic plant has a high medicinal and therapeutic potential and is commonly used as a painkiller. The medicinal properties of its essential oil and other extracts have been tested in rats and show edanalgesic, antiinflammatory, antioxidant, and vasodilator effects (SILVA et al, 2006;SANTOS et al, 2007;ANDRADE et al, 2010;MOREIRA et al, 2010;FRANCO et al, 2011;LIMA et al, 2013). Nevertheless, there are no Silva et al record sons the cultivation of this species.…”

Section: Introductionmentioning

confidence: 99%

Substrate composition and indolebutyric acid on the propagation of Eplingiella fruticosa from cuttings

2017

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Eplingiella fruticosa (Salzm. ex Benth.) Harley & J.F.B. Pastore, also known as â€œalecrim de vaqueiroâ€� or â€œcowboy rosemaryâ€�, is a woody, perennial, and aromatic shrub that growsin the states of northeast Brazil, with the exception of Alagoas, MaranhÃ£o, and PiauÃ. The plant is widely used in this region and has analgesic, vasodilator, anti-inflammatory, and larvicidal properties.The objective of this study was to evaluate the effect of different substrates and indolebutyric acid (IBA) on cuttings of E. fruticosa for identifying effective practices for the vegetative propagation of this species. Apical cuttings with a standardized length of 10cm and two pairs of leaves were harvested from mother plants in the vegetative stage. Two experiments were conducted: the first experiment tested the effect of three substrates (commercial, commercial + vermiculite, and commercial + vermiculite + humus) and the second experiment evaluated five concentrations of IBA (0.0, 1.0, 2.0, 3.0, and 4.0gLâˆ’1) and three growth periods (30, 45, and 60 days). The experimental design was randomized blocks with four replications. The analyzed variables were survival of cuttings, number of rooted cuttings, root length per cutting (RLC), number of buds per cutting (NBC), leaf dry mass (LDM), root dry mass (RDM), and total dry mass (TDM). In thefirst experiment,there were significant differences in RLC, NBC, LDM,RDM, and TDM, with a better growth using the commercial substrate. In the second experiment, there was no interaction between the evaluated parameters. However, there was a positive associated effect of IBA addition and the growth period on RLC, NBC, LDM, and RDM. The highest predicted value was attained for a concentration of 1.5g Lâˆ’1IBA and a growth period of 60 days, for the above-mentioned variables.

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“…It has been alleged that the Hyptis genus possesses medicinal properties and it is recommended in folk medicine for the treatment of several conditions, such as gastrointestinal disorders, skin infections, nasal congestion, fever and cramps (Rojas et al, 1992[ 43 ]). Additionally, redox, analgesic and anti-inflammatory profiles have been reported to this genus (Franco et al, 2011[ 12 ]; Lima et al, 2013[ 25 ]; Menezes et al, 2015[ 31 ]; Paixão et al, 2015[ 35 ], 2013[ 36 ]).…”

Section: Introductionmentioning

confidence: 99%

HPLC-DAD analysis, antinociceptive and anti-inflammatory properties of the ethanolic extract of Hyptis umbrosa in mice

Anjos

Araújo-Filho

Duarte

et al. 2017

EXCLI Journal; 16:Doc14; ISSN 1611-2156

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Orofacial antinociceptive effect and antioxidant properties of the hydroethanol extract of Hyptis fruticosa salmz ex Benth

Cited by 27 publications

References 28 publications

Research Article Assessment of genetic diversity of a native population of Eplingiella fruticosa: a plant with therapeutic potential.

Research Article Assessment of genetic diversity of a native population of Eplingiella fruticosa: a plant with therapeutic potential.

Substrate composition and indolebutyric acid on the propagation of Eplingiella fruticosa from cuttings

HPLC-DAD analysis, antinociceptive and anti-inflammatory properties of the ethanolic extract of Hyptis umbrosa in mice

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