Original article. The use of essential oils based antiseptic solution in the treatment of denture stomatitis

Abstract

Summary Introduction Local therapy of denture stomatitis (DS) associated with Candida species fungi infection usually involves the application of nystatin and miconazole. Due to the fact that these drugs may be less efficient against biofilm and possible resistance development, a new approach in the treatment includes the use of antiseptic agents. The aim of the study was to compare clinical and microbiological therapeutic outcomes of antiseptic solution Listerine® and Daktanol® antifungal oral gel in the treatment of DS associated with Candida species fungi. Material and Methods The study included 30 patients affected by DS, divided into the two treatment groups, control group (n=15) treated by Daktanol® gel and experimental group (n=15) treated by the antiseptic solution Listerine®. Successful treatment was evaluated based on palatal mucosa inflammation reduction classified according to the Newton classification and the difference in the number of fungal colony- forming units (CFU) isolated by smears before and after the treatment that lasted 14 days. Results Reduction in inflammation intensity and fungal CFU number on palatal mucosa (p<0,01) as well as on denture base (p<0,01) were observed in both groups of subjects after the treatment. Conclusion Antiseptic solution Listerine® and Daktanol® antifungal gel both reduced palatal mucosal inflammation and CFU number of fungi in mouth without significant differences among them. CFU number of fungi isolated from denture base was significantly lower after the treatment with Listerine® (p<0.05).

Composition’s effect of Origanum Syriacum essential oils in the antimicrobial activities for the treatment of denture stomatitis

“…EOs are used to disinfect dentures in mouthwash form [ 35 ], or when its major compound is incorporated into a soft liner [ 33 ]. The antimicrobial effectiveness of Os-O on denture materials should be further investigated before its clinical application in immersion form.…”

“…Listerine®) [34]. EO is used to decrease stomatitis in denture wearers [7,35]. Studies demonstrate that the Lebanese variety of Os-O exhibits a good antimicrobial activity against two of the most bacterial species that adhere to dentures: S. aureus and C. albicans [27,36].…”

Biofilm inhibition of denture cleaning tablets and carvacrol on denture bases produced with different techniques

“…It is available as mouthwash, consisting of a blend of several substances derived from various plant species [13]. EO helps those who wear dentures have less stomatitis [14,15].…”

Antimicrobial effect against oral microbiota after continuous use of natural oral spray products

“…Also, it disrupts metabolic processes dependent on microorganism membrane enzymes and also has anti-inflammatory effect. It acts against free unbound candida cells as well as against formed biofilm and it is shown to be more efficient than Daktanol® oral gel (2% miconazole, Galenika a.d. Belgrade, Serbia) (5) Essential oils also have an antibacterial effect against some cariogenic bacteria including Streptococcus mutans and Lactobacillus casei with minimal inhibitory concentration (MIC) values ranging from 31.2 to 500 mg/ml. Essential oil that extracts from Tetradenia riparia has a bactericidal effect against S. mutans for first 12 hours with direct cell contact similar to chlorhexidine dihydrochloride.…”