Origin of Wine Lignans

Dadáková, Kateřina; Jurasova, Lenka; Kašparovský, Tomáš; Průšová, Božena; Baroň, Mojmí­r; Sochor, Jiří­

doi:10.1007/s11130-021-00928-1

Cited by 5 publications

(3 citation statements)

References 29 publications

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“…Secoisolariciresinol, the lignan commonly found in flaxseeds, was also identified in all three grape pomace extracts with an increase in its relative content in the countercurrent method. The presence of secoisolariciresinol in wine has also been reported by Dadáková et al [80]. The liberation of this lignan from the grape cell matrix in the present study is likely due to alkaline hydrolysis, which has been widely used to release secoisolariciresinol from flaxseed complexes by cleaving ester linkages [81].…”

Section: Phenolic Composition Of Cabernet Sauvignon Grape Pomace Extr...supporting

confidence: 88%

Revitalizing Unfermented Cabernet Sauvignon Pomace Using an Eco-Friendly, Two-Stage Countercurrent Process: Role of pH on the Extractability of Bioactive Phenolics

et al. 2022

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As the major byproduct of the winemaking industry, grape pomace remains an untapped source of valuable bioactive phenolic compounds. This study elucidated the optimal aqueous extraction parameters for maximizing phenolic extractability, while avoiding the use of harsh conventional solvents and limiting water usage, from Cabernet Sauvignon grape pomace in which the red grape was processed for white wine. In the single-stage aqueous extraction process (AEP), the concurrent impact of pH (2.64–9.36), solids-to-liquid ratio (SLR, g pomace/mL water) (1:50–1:5), and temperature (41.6–58.4 °C) on the total phenolic content (TPC) of Cabernet Sauvignon pomace was evaluated alongside a kinetic study (15–90 min). Optimal single-stage extraction conditions (pH 9.36, 1:50 SLR, 50 °C, 75 min) guided the development of a two-stage countercurrent extraction process (pH 9.36, 1:10 SLR, 50 °C, 75 min) to further reduce water consumption without compromising overall extractability. The countercurrent process reduced fresh water usage by 80%, increased the TPC of the extracts by 18%, and improved the in vitro antioxidant activities (ABTS and ORAC) of the extracts. Untargeted metabolomics enabled the identification of a diverse pool of phenolics, especially flavonol glycosides, associated with grape pomace, while further phenolic quantitation detected improvements in the release of commonly bound phenolics such as ferulic acid, p-coumaric acid, syringic acid, and protocatechuic acid in alkaline extracts compared to the ethanolic extract. This investigation provides an efficient, eco-friendly extraction strategy suitable for applications in functional food, beverage, nutraceutical, and cosmetic industries.

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Section: Phenolic Composition Of Cabernet Sauvignon Grape Pomace Extr...supporting

confidence: 88%

Revitalizing Unfermented Cabernet Sauvignon Pomace Using an Eco-Friendly, Two-Stage Countercurrent Process: Role of pH on the Extractability of Bioactive Phenolics

et al. 2022

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“…The content of lignans in fruits is not high. The lignan content in fruits can vary significantly, ranging from negligible amounts in bananas to as high as 450 mg per 100 g in apricots. , Tea has been found to have the highest lignan content among nonalcoholic beverages. On average, red wines contain 80 μg/100 mL of lignan, while white wines have a lower lignan content of 22 μg/100 mL .…”

Section: Lignans Sources and Intakementioning

confidence: 99%

The What and Who of Dietary Lignans in Human Health: Special Attention to Estrogen Effects and Safety Evaluation

Li,

Ma,

Luo

et al. 2023

J. Agric. Food Chem.

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Lignans are a group of phenolic compounds found in plant-based diets. The human body can obtain lignans through diet, which are then metabolized into enterolignans. The enterolignans have been linked to several health benefits, including anticancer, anti-inflammatory, antioxidant effects, and estrogen effects. This review explores the relationship between the estrogenic effects of lignans and health. This review not only considers the estrogen-like activity of lignans but also discusses the safe dosage of lignans at different life stages. In addition, this review also identified other types of bioactive compounds that can act synergistically with lignans to promote health. Studies have shown that lignan administration during pregnancy and lactation reduces the risk of breast cancer in offspring. Further studies are needed to investigate the estrogenic safety effects of lignan on pregnant women and children. Whether lignans combine with other nutrients in complex food substrates to produce synergistic effects remains to be investigated. This review provides a basis for future studies on the safe dose of lignan and recommended dietary intake of lignan. We believe that the acquired as discussed here has implications for developing dietary therapies that can promote host nutrition and modulate estrogenic diseases.

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“…10,11 However, most of the literature is limited to the structural elucidation and/or bioactivity of isolated compounds or even a single compound. Only a few studies have relied on chromatographic profiling, such as liquid chromatography-mass spectrometry 12,13 or gas chromatography-mass spectrometry 14 or HPLC coupled with multiple-stage tandem mass spectrometry using electrospray ionization (HPLC-ESI-MS n ), 15,16 to obtain more comprehensive results, but numerous minor constituents remained undetected. Thus, the data on the detailed chemical profiles and relative abundances of lignans in Dendrobium are still lacking.…”

Section: Introductionmentioning

confidence: 99%

Identification of lignans and quality assessment in Dendrobium officinale under different cultivation modes

Zhang

et al. 2023

Rapid Comm Mass Spectrometry

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Rationale Lignans have attracted much attention from researchers because of their wide distribution and industrial applications in plants, as well as the remarkable diversity of their biological activities. As the literature has mainly focused on the extraction and identification of monomeric compounds of lignans, most lignans in Dendrobium officinale, a traditional Chinese medicine with a long cultivation history and rich sources, have not been detected using quality control methods. The aim of this study was to identify the lignans in Dactilon officinale. Methods High‐performance liquid chromatography (HPLC) coupled with diode array detection and HPLC multiple‐stage tandem mass spectrometry was used to identify the chemical constituents of D. officinale. Simultaneously, the characteristic chromatograms of D. officinale were established. Additionally, a method was established to determine the content of syringaresinol‐4,4′‐di‐O‐β‐D‐glucoside, syringaresinol‐4‐O‐β‐D‐glucoside and syringaresinol. Results Thirty‐three lignans, including 17 tetrahydrofuran lignans, two dibenzylbutane lignans, three aryl tetrahydronaphthalene lignans and 11 8‐O‐4′‐neolignans, were tentatively identified from the methanol extract of the stems of D. officinale. This is the first report of 8‐O‐4′‐neolignans from D. officinale. In addition, a total of eight characteristic peaks were marked in characteristic chromatograms, which were identified as lyoniresinol‐9′‐O‐β‐D‐glucoside, syringaresinol‐4,4′‐di‐O‐β‐D‐glucoside, 8‐hydroxy‐syringaresinol‐4‐O‐β‐D‐glucoside, 5,5′‐dimethoxy‐lariciresinol‐4‐O‐β‐D‐glucoside, syringaresinol‐4‐O‐β‐D‐glucoside, 4‐hydroxy‐3,3′,5,5′‐tetramethoxy‐8,4′‐oxyneoligna‐7′‐ene‐9,9′‐diol‐9‐O‐β‐D‐glucoside, 4‐hydroxy‐3,3′,5,5′‐tetramethoxy‐8,4′‐oxyneoligna‐7′‐ene‐9,9′‐diol‐4‐O‐β‐D‐glucoside and syringaresinol. Our results showed that no significant difference occurred in lignan composition among the 99 batches of D. officinale from different sources. However, the peak areas of the lignans of D. officinale planted under simulated wild culture were generally higher than those in greenhouses, and showed an upward trend with the increase in growth years. The average contents of syringaresinol‐4,4′‐di‐O‐β‐D‐glucoside, syringaresinol‐4‐O‐β‐D‐glucoside and syringaresinol were 10.112–179.873, 51.227–222.294 and 6.368–120.341 μg/g, respectively. Conclusions This study provided a basis for improving the quality control of D. officinale and could provide references for the identification of lignans in other Dendrobium species.

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Origin of Wine Lignans

Cited by 5 publications

References 29 publications

Revitalizing Unfermented Cabernet Sauvignon Pomace Using an Eco-Friendly, Two-Stage Countercurrent Process: Role of pH on the Extractability of Bioactive Phenolics

Revitalizing Unfermented Cabernet Sauvignon Pomace Using an Eco-Friendly, Two-Stage Countercurrent Process: Role of pH on the Extractability of Bioactive Phenolics

The What and Who of Dietary Lignans in Human Health: Special Attention to Estrogen Effects and Safety Evaluation

Identification of lignans and quality assessment in Dendrobium officinale under different cultivation modes

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