Origin of tradeoff between movement velocity and attachment duration of kinesin motor on a microtubule
Yuying 玉颖 Liu 刘,
Zhiqiang 志强 Zhang 张
Abstract:Kinesin-1 motor protein is a homodimer containing two identical motor domains connected together by a common long coiled-coil stalk via two flexible neck linkers. The motor can step on microtubule with a velocity of about 1 μm/s and an attachment duration of about 1 s under the physiological condition. The available experimental data indicated the tradeoff between the velocity and attachment duration under the variation of different experimental conditions, such as the variation of the solution temperature, th… Show more
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