Abstract:To investigate individuals heterozygous for reciprocal translocations is one object of prenatal diagnosis because of the high risks inherent in chromosomally unbalanced offspring (Bou6 and Gallano, 1984;Daniel et al., 1988). In genetic counseling, it is important to estimate the percentage risk of having such offspring (Fuhrmann and Vogel, 1982;Harper, 1988)~ The risks may depend on events including various ratios of cells with an unbalanced chromosome constitution resulting from segregation from quadrivalents… Show more
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