Abstract:resumenLos primeros programas de cribado neonatal de errores congénitos del metabolismo y otras enfermedades endocrinas comenzaron a finales de los años cincuenta y, una década más tarde, se introdujeron en España. Desde entonces han evolucionado mucho, pero de forma muy heterogénea, tanto a nivel internacional como autonómico. Los continuos avances científicos y tecnológicos, fundamentalmente desde el año 2000, han hecho que estas desigualdades se acentúen, haciendo de este tema un inagotable asunto de revisi… Show more
“…A su vez, los buenos hábitos higiénicos de sueño y la práctica de ejercicio físico están asociados con menor prevalencia de síndrome de burnout en colectivos que desarrollan igual tarea, constituyendo auténticos hábitos preventivos laborales 8 .…”
“…A su vez, los buenos hábitos higiénicos de sueño y la práctica de ejercicio físico están asociados con menor prevalencia de síndrome de burnout en colectivos que desarrollan igual tarea, constituyendo auténticos hábitos preventivos laborales 8 .…”
“…PKU is one of the universal diseases included in the neonatal screening that meets all the screening criteria and justifies all the associated costs [6]. In Spain, it was the first disease included in the national neonatal screening in 1968 [7]. The early detection of this disease and the treatment at birth prevents neurocognitive damage.…”
Background: Phenylketonuria (PKU) is a well-known rare disease which is included in the neonatal screening of many countries. Therefore there are few published data on the admissions and cost in Spain.Objective: To assess the number of admissions and economic burden of PKU in Spain.Methods: PKU patients were identified from a Spanish database containing data from public and private healthcare centres from 1997 to 2015. The parameters obtained were: characteristics of the patients, type of admissions, readmissions, discharge, length of stay, medical service, annual number of visits, annual number of patients, visit associated costs and patient associated costs.Results: 594 PKU patients were identified: 48.32% were males with a mean (SD) age of 4.50 (10.23) years. The hospital admissions were divided into emergency visits (55.94%) and scheduled visits (43.92%). Most of the discharges were at home (98.86%). The mean (SD) duration of stay was 4.04(4.98) days.
Background: Phenylketonuria is a well-known disease, yet the characteristics of the affected population and their use of healthcare resources have not been comprehensively evaluated. Patient characteristics and use of resources are subjects of interest for most governments, especially for a disease included in new born screening programs. Objective: The aim of this study was to determine characteristics and use of healthcare resources of patients with phenylketonuria in the region of Catalonia. Methods: Records of 289 patients admitted with phenylketonuria between 2007 and 2017 were extracted from the PADRIS database that includes admission data from primary care centers, hospitals (inpatient and outpatient care), extended care facilities and mental health centers. Results: Patient population was composed by 140 males and 149 females, and 102 patients were registered via newborn screening during the study period. Patients were admitted on average 2.19 times per year, mostly into primary care centers which concentrated the biggest portion of direct medical expenses. Similar percentages of urgent and scheduled admissions were registered both in primary care and hospitals. Annual direct medical cost of treating patients with PKU was €667 per patient. Finally, 66.80% of the patients suffered from chronic conditions affecting 2 or more systems, likely to correspond to a wide variety of conditions. Conclusions: Altogether, phenylketonuria patient demographics and direct medical costs in Catalonia have been revised. Patients diagnosed with phenylketonuria appeared 1.3 times more likely to suffer from chronic conditions in distinct organ systems, which is expected to have an effect on their use of healthcare resources. These results support the need to adapt and improve the health care system taking multimorbidity into consideration in an effort to control the medical expenses derived.
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