Origin and flow-mediated remodeling of the murine and human extraembryonic circulation systems
Kristof Van Schoor,
Emmanuel Bruet,
Elizabeth Anne Vincent Jones
et al.
Abstract:The transduction of mechanical stimuli produced by blood flow is an important regulator of vascular development. The vitelline and umbilico-placental circulations are extraembryonic vascular systems that are required for proper embryonic development in mammalian embryos. The morphogenesis of the extraembryonic vasculature and the cardiovascular system of the embryo are hemodynamically and molecularly connected. Here we provide an overview of the establishment of the murine and human vitelline and umbilico-plac… Show more
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