“…The general applicability of this method is illustrated by the fact that numerous naturally occurring isoflavones were synthesized using this procedure. This method became popular almost immediately and was successfully used by numerous research groups [88][89][90][91][92][93][94][95][96][97][98][99][100][101] for the synthesis of variously substituted isoflavones 6. In some cases the 2-carbethoxyisoflavones have also been utilized in the drug research [99,100].…”
Section: Synthesis and Decarboxylation Of 2-carboxyi S O F L A V O mentioning
“…The general applicability of this method is illustrated by the fact that numerous naturally occurring isoflavones were synthesized using this procedure. This method became popular almost immediately and was successfully used by numerous research groups [88][89][90][91][92][93][94][95][96][97][98][99][100][101] for the synthesis of variously substituted isoflavones 6. In some cases the 2-carbethoxyisoflavones have also been utilized in the drug research [99,100].…”
Section: Synthesis and Decarboxylation Of 2-carboxyi S O F L A V O mentioning
“…This method became popular almost immediately and was successfully used by numerous research groups [88][89][90][91][92][93][94][95][96][97][98][99][100][101] for the synthesis of variously substituted isoflavones 6. However, this fact does not result in any difficulty since these ethoxalyl groups are removed on the acidification of the reaction mixture with a dilute acid to provide 2-carbethoxyisoflavones 7 with free hydroxyl groups.…”
Section: Synthesis and Decarboxylation Of 2-carboxyi S O F L A V O mentioning
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