Organotin polymers as anticancer and antiviral agents

Two new organotin(IV)-phosphoryl complexes: crystal structure and Hirshfeld surface analysis

“…Tin complexes are of great interest because of their unique properties in medicine, industrial applications and biological systems [1][2][3][4]. Among which the tin-phosphoryl complexes have received considerable attention due to the diverse structural features known for phosphoryl-donor ligands [5] and various applications such as anti-bacterial [6], anti-HIV [7] and anti-cancer [8] activities and also agricultural uses [9] and enzyme inhibitory [10] for phosphoryl compounds.…”

“…Up to now, different families of phosphoryl compounds, with different coordination environment at the P atom Abstract Hirshfeld surfaces and two-dimensional fingerprint plots are used to visualize and analyse intermolecular interactions in two new organotin(IV)-phosphoryl complexes: [Sn(CH 3 ) 2 4 environment with the axial positions occupied by methyl groups and with the oxygen atoms of Sn-O bonds located at the equatorial plane, while the oxygen atoms of OCH 3 groups do not take part in the coordination interaction. In (II), the asymmetric unit contains one complete molecule and the tin centre has an Sn[C] 2 [Cl] 2 O trigonal bipyramid coordination environment, where the phosphoric triamide ligand and one of the chlorine atoms are placed in axial positions.…”

“…In (II), the asymmetric unit contains one complete molecule and the tin centre has an Sn[C] 2 [Cl] 2 O trigonal bipyramid coordination environment, where the phosphoric triamide ligand and one of the chlorine atoms are placed in axial positions. Hirshfeld surface analysis on the asymmetric unit of (I) shows a contribution of 5.9 % of total interactions in crystal for Sn…O contacts related to involving of four-coordinated Sn site of asymmetric unit with two oxygen atoms of two neighbouring phosphates in the coordination polymer.…”

“…In this work, we report two complexes of organotin(IV): a novel one-dimensional coordination polymer with the formula [Sn(CH 3 ) 2 [33].…”

Dialkyltin(IV)bis(O–tolyl/benzyldithiocarbonate) complexes: Spectroscopic, thermogravemetric, antifungal and crystal analysis of n–Bu2Sn(S2COCH2C6H5)2

“…14 Over the years, a variety of uses have been found for organic and inorganic tin compounds as fungicides, 15 moluscicides 16 and stabilizers in plastics. 17 The organotin complexes exhibit a wide range of biological activities [18][19][20] including the inhibition of a wide variety of cancer cell lines including cell lines associated with ovarian, colon, lung, prostrate, pancreatic and breast cancer. 20 Recently there have been a number of concerns raised regarding possible human health effects associated with organotins such as the use of tributyltin (TBT) in paints caused contamination in coastal waters and marine sediments.…”