Organotin(IV) 4-nitrophenylethanoates: Synthesis, structural characteristics and intercalative mode of interaction with DNA

Electrochemical investigations of unexplored anthraquinones and their DNA binding

“…All supporting electrolyte solutions (Table 1) were prepared using analytical grade reagents. Double stranded DNA was extracted from chicken blood by Falcon method [15,16]. The concentration of the DNA stock solution (2.0 mM) was determined from UV absorbance at 260 nm using a molar extinction coefficient (ε) of 6600 M −1 cm −1 [17,18].…”

Thermal Decomposition Kinetics of Some Di‐ and Triorganotin(IV) Carboxylates Derived from para‐Nitrophenylethanoic Acid

“…These results are in agreement with earlier reports. 28,30 Synthesis and characterization of the compounds 2, 3, 5 and 6 have already been discussed elsewhere 28 whereas for the others they are detailed as below.…”

“…Among these formulations of tin, the derivatives of methyl, ethyl and butyl are found to have a considerable activity against cancerous prostate cell lines (PC-3), providing a strong mode of interaction with DNA. 28 It is believed that thermal characterization of the compounds will be useful to provide a better understanding on the chemistry of compounds for future developments.…”

Fluoro Substituted Monomeric and Uni-Dimensional Polymeric Organotin(IV) Esters of (E)-4-oxo-4-((3-trifluoromethyl)phenyl)amino)but-2-enoic acid; Synthesis, Characterization and Their In vitro Inhibitory Studies

“…Organotin carboxylates have been the subject of great interest due to potential antibacterial, antifungal, anticancer agents and structural diversity [3][4][5]. The ambidentate nature of ligands attached [6], substitution on tin/acid and weaker interactions like hydrogen bonding are significant features that describe the tendency of complexes to bind with proteins [7]. Moreover, an increase in the donor sites in the ligand and inclusion of a highly electronegative substituent like trifluoromethyl groups can optimize interactions with DNA proteins [7].…”

“…The ambidentate nature of ligands attached [6], substitution on tin/acid and weaker interactions like hydrogen bonding are significant features that describe the tendency of complexes to bind with proteins [7]. Moreover, an increase in the donor sites in the ligand and inclusion of a highly electronegative substituent like trifluoromethyl groups can optimize interactions with DNA proteins [7]. Previously, fluorine-substituted organotin(IV) complexes containing mono-or polyfunctional groups have been reported [8][9][10][11].…”