Organosilanes and their magnetic nanoparticles as naked eye red emissive sensors for Ag⁺ ions and potent anti-oxidants

Abstract

The present article reports the synthesis and structural characterization of triazole appended isatin linked silane-based sensor using highly efficient click chemistry approach. The yellow-coloured solution of highly selective chemosensor turned...

Heterocycle-derived organosilatranes as naked eye sensors for Sn2+ ions and their potential inhibiting activity against HIV-1 protease via a computational approach

“…Schiff bases have been investigated as promising potential drugs such as anti-cancer, antibacterial, and antifungal drugs as well as in scientific fields such as automobiles, graphic design, fabric and imaging technology. 27 Silatranes are cyclic ethers of trialkanolamines with the general formula XSi (OCR 2 CR 2 ) 3 N, a kind of tricyclic cage having a transannular dative bond between the silicon and nitrogen atom, which provides stability compared to their open-chain counterparts i.e., trialkoxysilanes, therefore reducing the sensitivity to hydrolysis. 28,29 The area of silatranes is fast progressing, being employed as materials research objects and powerful biological active agents in biology and medicine for anti-bacterial, antiinflammatory and anti-cancer activities.…”

Development of Isatin‐Based Schiff Bases Targeting VEGFR‐2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies

“…In the continuous effort of our research group to develop potential drug candidates for cancer, [20,21] we utilized the isatin scaffold to synthesize various Schiff bases. Isatin-based Schiff bases are reported for diverse pharmacological properties such as analgesic, [22,23] anti-inflammatory, [24][25][26] antimicrobial, [27][28][29] antioxidant, [30][31][32][33] anticonvulsant, [34][35][36] and most predominantly, anticancer [37][38][39][40] properties. In addition, reported studies of isatin Schiff bases as VEGFR-2 inhibitors are encouraging.…”

Positional Isomeric Symmetric Dipodal Receptors Dangled with Rotatable Binding Scaffolds: Fluorescent Sensing of Silver Ions and Sequential Detection of l-Histidine and Their Multifarious Applications

“…Tons of silver ions from domestic usage and industries percolate and slowly spread over natural surroundings and accumulate in our environment, leading to several health problems. As a result, silver is a major heavy metal polluter in the environment and is very hazardous to biological systems. − Despite this, silver is a well-known metal ion for its appealing surface glossy look in the manufacturing of silverware, coins, and jewelry. − Silver ions/silver nanoparticles have garnered substantial attention from ancient times to the present day due to their potential biological properties, particularly antibacterial capabilities. , The World Health Organization (WHO) and the U.S. Environmental Protection Agency (EPA) have determined safe limits of silver in drinking water and the human body at 0.05 ppm and 0.05 mg/L, respectively. Silver ions bioaccumulate in the human body via the regular food chain and drinking water.…”