Suicidal poisoning with pesticides in humans is common in India. Despite the interdiction or regulation of several pesticides, there are reported considerate poisoning cases in India. Pyridaben is a potentially fatal insecticide with extreme neurotoxicity in humans. Pyridaben toxicity reports in humans are uncommon. Here we describe a case of acute poisoning with Pyridaben in a minor girl who presented with severe nausea, vomiting, altered consciousness, body weakness, abdomen pain, and congestion of visceral organs. Soon after the poisoning, the patient was treated with life-saving mechanical ventilation. Forensic examination of the viscera of a minor victim enlightened that the death was assignable to Pyridaben intoxication. GC-MS analysis of viscera showed significant results in concern to the identification of Pyridaben. The present case study emphasized the misuse of readily accessible pesticides and identified a new pesticide that can exert a deleterious impact on human health deliberately (suicide) and unintentionally (accidental) exposure. The same needs to be communicated to the scientific community to explore this lethal pesticide for its all-possible detrimental impacts consequently gathering scientific evidence in this regard will abet to regulate it by legislative.