Organophosphate Pesticide Exposure and Glucose Homeostasis

Abstract

Present review discusses the organophosphate (OP) pesticides toxicity with associated hyperglycemia in animal as well as human studies and effect of OP pesticide on liver enzymes involved in glucose homeostasis pathways. Pancreas keeps hormonal control of glucose homeostasis by secretion of glucagon and insulin. Insulin resistance is higher risk of impair glucose homeostasis. Based on cumulative evidences, oxidative stress induced by OP pesticides may lead to disturbance of glucose homeostasis. There is increasing interest in environment pesticides exposure can affect the glucose homeostasis.fasciculation [10]. During these conditions, the flow of oxygen through brain and muscle is greatly increased. This metabolic stress Volume 14-Issue 2