Organogenesis in plants: initiation and elaboration of leaves

Sluis, Aaron; Hake, Sarah

doi:10.1016/j.tig.2015.04.004

Cited by 73 publications

(57 citation statements)

References 93 publications

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“…Recent studies have uncovered an even higher potential for prolonged morphogenesis in tomato leaf development, which is normally restricted by differentiation-promoting factors (Bar et al, 2015;Shani et al, 2010;Yanai et al, 2011). Characterization of mutants with extended or restricted morphogenesis has pointed to this potential and led to the identification of factors that balance morphogenesis and differentiation during leaf development (Sluis and Hake, 2015;Canales et al, 2010;Efroni et al, 2010;Bar and Ori, 2014;Blein et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

CLAUSA is a MYB Transcription Factor that Promotes Leaf Differentiation by Attenuating Cytokinin Signaling

et al. 2016

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Leaf morphogenesis and differentiation are highly flexible processes, resulting in a large diversity of leaf forms. The development of compound leaves involves an extended morphogenesis stage compared with that of simple leaves, and the tomato (Solanum lycopersicum) mutant clausa (clau) exposes a potential for extended morphogenesis in tomato leaves. Here, we report that the CLAU gene encodes a MYB transcription factor that has evolved a unique role in compound-leaf species to promote an exit from the morphogenetic phase of tomato leaf development. We show that CLAU attenuates cytokinin signaling, and that clau plants have increased cytokinin sensitivity. The results suggest that flexible leaf patterning involves a coordinated interplay between transcription factors and hormones.

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Section: Introductionmentioning

confidence: 99%

CLAUSA is a MYB Transcription Factor that Promotes Leaf Differentiation by Attenuating Cytokinin Signaling

et al. 2016

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“…Numerous factors, including transcription factors, miRNAs and hormones control leaf development (Bar and Ori, 2014;Rodriguez et al, 2014;Sluis and Hake, 2015). Transcription factors of the CUP-SHAPED COTYLEDON2 (CUC2) family, for example, have a central role in the dissection of the leaf margin into teeth or leaflets (Nikovics et al, 2006;Blein et al, 2008;Berger et al, 2009;Kawamura et al, 2010;Bilsborough et al, 2011;Hasson et al, 2011;Cheng et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Multiscale quantification of morphodynamics: MorphoLeaf, software for 2-D shape analysis

et al. 2016

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A major challenge in morphometrics is to analyse complex biological shapes formed by structures at different scales. Leaves exemplify this challenge as they combine differences in their overall shape with smaller shape variations at their margin leading to lobes or teeth. Current methods based on contour or on landmarks analysis are successful in quantifying either overall leaf shape or leaf margin dissection, but fail in combining the two. Here, we present a comprehensive strategy and its associated freely available platform for the quantitative, multiscale analysis of the morphology of leaves with different architectures. For this, biologically relevant landmarks are automatically extracted and hierarchized, and used to guide the reconstruction of accurate average contours that properly represent both global and local features. Using this method we established a quantitative framework of the developmental trajectory of Arabidopsis leaves of different ranks and retraced the origin of leaf heteroblasty. When applied to different mutant forms our method can contribute to a better comprehension of gene function as we show here for the role of CUC2 during Arabidopsis leaf serration. Finally, we illustrated the wider applicability of our tool by analysing hand morphometrics.

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“…Leaf growth in plants is initiated at shoot meristems (for review, see Sluis and Hake 2015). After specification of boundaries and growth axes, the leaf lamina grows in an initial period of cell division in which cell size is relatively constant, followed by a transition to endoreduplication associated with cell expansion and differentiation (Breuer et al 2010;De Veylder et al 2011).…”

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confidence: 99%

Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis

et al. 2017

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The characteristic shapes and sizes of organs are established by cell proliferation patterns and final cell sizes, but the underlying molecular mechanisms coordinating these are poorly understood. Here we characterize a ubiquitinactivated peptidase called DA1 that limits the duration of cell proliferation during organ growth in Arabidopsis thaliana. The peptidase is activated by two RING E3 ligases, Big Brother (BB) and DA2, which are subsequently cleaved by the activated peptidase and destabilized. In the case of BB, cleavage leads to destabilization by the RING E3 ligase PROTEOLYSIS 1 (PRT1) of the N-end rule pathway. DA1 peptidase activity also cleaves the deubiquitylase UBP15, which promotes cell proliferation, and the transcription factors TEOSINTE BRANCED 1/CYCLOIDEA/ PCF 15 (TCP15) and TCP22, which promote cell proliferation and repress endoreduplication. We propose that DA1 peptidase activity regulates the duration of cell proliferation and the transition to endoreduplication and differentiation during organ formation in plants by coordinating the destabilization of regulatory proteins.

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Organogenesis in plants: initiation and elaboration of leaves

Cited by 73 publications

References 93 publications

CLAUSA is a MYB Transcription Factor that Promotes Leaf Differentiation by Attenuating Cytokinin Signaling

CLAUSA is a MYB Transcription Factor that Promotes Leaf Differentiation by Attenuating Cytokinin Signaling

Multiscale quantification of morphodynamics: MorphoLeaf, software for 2-D shape analysis

Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis

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