2016
DOI: 10.1016/j.reprotox.2016.06.017
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Organochlorine pesticides and female puberty in South Kazakhstan

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Cited by 36 publications
(12 citation statements)
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References 30 publications
(31 reference statements)
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“…Unsafe use of pesticides may lead to different types of cancer (3), congenital defects, impairment of central nervous system, respiratory diseases, skin diseases, endocrine system (4), weakness of body immune system (2), infertility (5), increase of chronic diseases, congenital disorders (6), delayed puberty in girls (7), intoxication (8), psychological adverse effects on the aspects of farmers lives such as quality of life, depression, anxiety, and stress (5), as well as increase of mortality rate in agricultural workers and their family members especially among children (9).…”
Section: Introductionmentioning
confidence: 99%
“…Unsafe use of pesticides may lead to different types of cancer (3), congenital defects, impairment of central nervous system, respiratory diseases, skin diseases, endocrine system (4), weakness of body immune system (2), infertility (5), increase of chronic diseases, congenital disorders (6), delayed puberty in girls (7), intoxication (8), psychological adverse effects on the aspects of farmers lives such as quality of life, depression, anxiety, and stress (5), as well as increase of mortality rate in agricultural workers and their family members especially among children (9).…”
Section: Introductionmentioning
confidence: 99%
“…By contrast, a review conducted by Perry [29] that evaluated low-level occupational exposure to a variety of pesticides concluded that epidemiologic evidence is far equivocal due to the small number of published studies. In another study, Bapayeva et al [30] assessed the puberty of females living in cotton-growing regions where organochlorine pesticides are widely used. The study showed the adverse effect of organochlorine pesticides on the development of the female reproductive system during puberty.…”
Section: Resultsmentioning
confidence: 99%
“…Некоторые ХОС проявляют эстрогенстимулирующее действие [28], которое может являться как АУР-опосредованной [15], так и прямой активацией эстрогенных рецепторов [28]. Необходимо отметить, что некоторые ЭДС обладают антиэстрогенным действием, блокируя сигналы с эстрогенного рецептора [8]. Мониторинг концентрации эстрогенов у жительниц Приаралья показал низкие концентрации этих гормонов [8].…”
Section: обсуждения результатовunclassified
“…Необходимо отметить, что некоторые ЭДС обладают антиэстрогенным действием, блокируя сигналы с эстрогенного рецептора [8]. Мониторинг концентрации эстрогенов у жительниц Приаралья показал низкие концентрации этих гормонов [8].…”
Section: обсуждения результатовunclassified
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