Organochlorine pesticide residues in human milk and estimated daily intake (EDI) for the infants from eastern region of Saudi Arabia

Hajjar, M. Jamal; Al-Salam, Ahmad

doi:10.1016/j.chemosphere.2016.09.013

Cited by 18 publications

(3 citation statements)

References 18 publications

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“…Breast milk collected in Korea in 2011 showed OCP levels of 91.7, 20.5, 6.51, 2.22, and 0.94 ng·g −1 ·lipid −1 for p,p ′-DDT, β-HCH, p,p ′-DDD, heptachlor epoxide, and p,p ′-DDE, respectively [ 29 ]. In other developing Asian countries like India and Saudi Arabia, among all the available commercial products with OCPs, only γ-HCH is permitted to be used for agricultural purposes, which is a possible reason for its higher mean concentrations of 0.37, 0.35, 0.35, and 0.29 mg·L −1 in four cities (Al-Hassa, Al-Khobar, Al-Jubail, and Al-Dammam, respectively) where HCH was dominant in the breast milk samples [ 30 , 31 ]. Therefore, this study shows the OCP levels in Taiwan to be lower than those in the neighboring countries ( Table 6 ).…”

Section: Discussionmentioning

confidence: 99%

Association between Organochlorine Pesticide Levels in Breast Milk and Their Effects on Female Reproduction in a Taiwanese Population

Chen

Santos

Que

et al. 2018

IJERPH

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Only few studies have focused on organochlorine pesticides (OCPs) in breast milk and the related health risks for women in Taiwan. Our goal is to examine breast milk OCPs and their associations with female reproductive function (infertility, gynecological diseases, and menstruation characteristics) as well as their correlation with sociodemographic parameters (age, pre-pregnant body mass index (BMI), annual incomes, population, birth year, and parity) and dietary habit. The breast milk samples were collected in southern Taiwan (n = 68) from 2013 to 2016 and the OCP residues were analyzed using high resolution gas chromatography with low resolution mass spectrometry (HRGC/LRMS). The results show that the most abundant OCP residues in the breast milk was ΣDDT with the geometric mean ± standard deviation of 9.81 ± 7.52 ng−1 lipid−1 followed by ΣHCH (0.539 ± 0.557 ng−1·lipid−1). In the principal component analysis, cis-chlordane (cis-CHL) and γ-HCH were found to be related to participants who received medical treatment for infertility, and 4,4′-DDT was associated with those who received gynecological surgery. The logistic regression showed that the odds ratio (OR) of log γ-hexachlorocyclohexane (γ-HCH) was higher for mothers who had received medical treatment for infertility than for the normal group (OR = 25.6, p = 0.035) after adjustments for age, pre-pregnant BMI, annual income, population (i.e., native-born Taiwanese), birth year, and parity. Cow milk and beef consumption as well as menstruation characteristics such as average menstrual period (>5 days), shortest menstrual period (<3 days), and women who had taken hormonal drugs were significantly associated to several OCP residues in the breast milk. In addition, ΣHCH including β-HCH and γ-HCH was correlated with annual family income and gravidity as well as cow milk and beef consumptions. Overall, γ-HCH exhibited a probable association with the infertility diseases of Taiwanese women, and dietary habit might play an important role in the female Taiwanese exposure to OCPs.

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Section: Discussionmentioning

confidence: 99%

Association between Organochlorine Pesticide Levels in Breast Milk and Their Effects on Female Reproduction in a Taiwanese Population

Chen

Santos

Que

et al. 2018

IJERPH

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“…Además, pueden entrar en la cadena alimentaria debido a su estructura química hidrofóbica (2) Entre 1940 y 1970, los pesticidas organoclorados fueron ampliamente utilizados en el manejo de la salud pública de plagas agrícolas e insectos transmitidos en la mayoría de los países del mundo (5). La aplicación continua de este pesticida contra plagas de insectos ha provocado efectos tóxicos en el medio ambiente y una gran acumulación de residuos en la agricultura y los productos lácteos (10).…”

Section: Resultsunclassified

Residuos tóxicos en leche materna: revisión de la literatura

Calderón¹,

Sánchez

2022

PFR

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Los pesticidas son productos químicos que se utilizan principalmente en la agricultura para proteger las plantas de plagas, malezas o enfermedades, y en los programas de protección de la salud pública para proteger a los seres humanos de las enfermedades transmitidas por vectores, como malaria, dengue y esquistosomiasis. El uso persistente y la exposición contribuyen a la contaminación del medio ambiente y del cuerpo humano. La bioacumulación de los plaguicidas organoclorados en el tejido adiposo desencadena la excreción en la leche materna durante la lactancia. Se realizó una revisión bibliográfica de artículos originales escritos en español o inglés. La búsqueda se realizó en las bases de datos Medline, Science Direct y Epistemonikos. No se hicieron restricciones respecto al tipo de estudio. Por ser la leche humana el alimento idóneo para el neonato, es fundamental analizar los factores que determinan la presencia de residuos y contaminantes en la misma. El presente trabajo tiene la finalidad de permitir la comprensión de este importante tema, así como incentivar a la investigación clínica en el medio local debido a la incidencia de uso de mencionados productos y plantear intervenciones para evitar consecuencias en la salud pública.

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“…A research carried out in 2016 in Saudi Arabia noticed organochlorinated compounds HEP, DLD and END presented levels in human milk enough to exceed recommended acceptable daily intake values (set as 0.1 µg kg −1 body weight day −1 ) (HAJJAR, AL-SALAM, 2016).…”

Section: Latest Twenty Years Of Pcbs and Ocps Contamination In Milkmentioning

confidence: 99%

Analytical developments for organochlorinated compounds determination in milk

Marques¹

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Organochlorine pesticide residues in human milk and estimated daily intake (EDI) for the infants from eastern region of Saudi Arabia

Cited by 18 publications

References 18 publications

Association between Organochlorine Pesticide Levels in Breast Milk and Their Effects on Female Reproduction in a Taiwanese Population

Association between Organochlorine Pesticide Levels in Breast Milk and Their Effects on Female Reproduction in a Taiwanese Population

Residuos tóxicos en leche materna: revisión de la literatura

Analytical developments for organochlorinated compounds determination in milk

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