Organizing pneumonia secondary to Pneumocystis jirovecii infection in a kidney transplant recipient: Case report and review of literature

Kodati, Rakesh; Tadepalli, Anuradha; Reddy, C Mallikarjuna; Chakravarthi, Rajasekhara; Kumthekar, Girish; Tagore, Ravindranath

doi:10.4103/lungindia.lungindia_487_19

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Similarly, pulmonary mucormycosis which has nearly 100% mortality in RT patients, was managed with surgical resection and antifungals in the perioperative period; this along with decreased immunosuppression post-RT lead to a favorable outcome of RT in ten Indian patients [ 46 ]. Infection with Pneumocystis jirovecii , though uncommon due to universal usage of cotrimoxazole in post-transplant period, was noticed as organizing pneumonia towards the end of prophylaxis therapy in an Indian patient of RT on triple immunosuppression [ 47 ].…”

Section: Ifi In Sot: India Vs the Worldmentioning

confidence: 99%

Epidemiology of Invasive Fungal Infections in Solid Organ Transplant Recipients: an Indian Perspective

Sharma

Rudramurthy

Chakrabarti³

2022

Curr Fungal Infect Rep

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Purpose of Review This review summarizes the available Indian data on epidemiology of invasive fungal infections (IFI) in recipients of solid organ transplants (SOT). The epidemiology is further compared with studies from other parts of the world for each SOT type. Recent Findings The available studies on Indian epidemiology of IFI in SOT are scarce, though the number of SOTs performed in India have increased tremendously in recent years. The limited data from India present a distinct spectrum of infection in transplant recipients with high incidence of mucormycosis. During COVID-19 outbreak, IFI rate increased and renal transplant recipients acquired mucormycosis earlier than previous studies. Summary Maximum data on IFI was available from renal transplant recipients, wherein mucormycosis was the predominant IFI in Indian patients in contrast to invasive candidiasis in majority countries. The other IFIs had varied spectrum. With the increasing number of SOTs being performed and the already persisting high burden of IFI in India, there is an urgent need of larger prospective studies on epidemiology of IFI in transplant recipients.

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Section: Ifi In Sot: India Vs the Worldmentioning

confidence: 99%

Epidemiology of Invasive Fungal Infections in Solid Organ Transplant Recipients: an Indian Perspective

Sharma

Rudramurthy

Chakrabarti³

2022

Curr Fungal Infect Rep

View full text Add to dashboard Cite

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Post-CMV organizing pneumonia – An unusual presentation 10 years after kidney transplantation

Gaur¹,

Singhal²,

Verma³

et al. 2022

Indian J Nephrol

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A 45-year-old gentleman underwent kidney transplantation in March 2010. He remained apparently healthy for the next 10 years when he developed anorexia and weight loss. Diagnostic workup revealed cytomegalovirus (CMV) pneumonia. While viremia resolved within 3 weeks of initiation of valganciclovir, he developed progressive breathlessness and hypoxia on exertion. Imaging of thorax revealed central peri-bronchovascular consolidation and fine reticulations with peripheral sparing. Computed tomography (CT)-guided percutaneous lung biopsy revealed organizing intra-alveolar exudates, suggestive of organizing pneumonia, with no evidence of active infection on biopsy as well as bronchoalveolar lavage (BAL) cytology. This atypical pattern of central distribution of opacities is not typical of organizing pneumonia where peripheral subpleural distribution is more common. Patient responded dramatically following escalation of steroids, with complete resolution of infiltrates on follow-up imaging.

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Organizing pneumonia secondary to Pneumocystis jirovecii infection in a kidney transplant recipient: Case report and review of literature

Cited by 2 publications

References 17 publications

Epidemiology of Invasive Fungal Infections in Solid Organ Transplant Recipients: an Indian Perspective

Epidemiology of Invasive Fungal Infections in Solid Organ Transplant Recipients: an Indian Perspective

Post-CMV organizing pneumonia – An unusual presentation 10 years after kidney transplantation

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