This chapter focuses on the interplay between information technology and organizational systems. It introduces the volume, providing a brief overview of some of the most relevant frameworks, approaches, and tools in the IS field which will be discussed later. The volume is divided into II parts, each one focused on a specific theme, such as 'ICT, organizational innovation and change' and 'ICT and knowledge management'.This book explores a range of critical issues and emerging topics relevant to the linkages between information technology and organizational systems. It encourages debate and opens up new avenues of inquiry in the field of Information Systems, organization and management studies, by investigating themes of growing research interest from multiple disciplinary perspectives such as organizational innovation and impact, information technology, innovation transfer, and knowledge management.The title of this book, 'Managing Information and Technology for Organizational Innovation and Change', already implies the understanding that information and technology are two crucial factors for developing innovation and for managing change within organizational contexts. Information and technology were widely recognised by the managerial literature as a major source of competitive advantage and increased business performance [1,2]. In the last decades, organizations have increasingly invested in Information and Communication Technology (ICT) for improving their efficiency and effectiveness and thus for providing an opportunity for their businesses. Indeed, ICTs were often recognized as a way to develop organizational innovation and to lead organizational change [3][4][5][6]. However, empirical experience has immediately shown that ICT adoption is