Organization of cervical cancer screening with DNA–HPV testing impact on early–stage cancer detection: a population–based demonstration study in a Brazilian city

Vale, Diama Bhadra; Campos, Cirbia Silva; Bragança, Joana Fróes; Discacciati, Michelle Garcia; Zeferino, Luíz Carlos

doi:10.1016/j.lana.2021.100084

Cited by 17 publications

(22 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Related research shows that HPV testing has higher coverage and better age compliance than Pap smears in early cervical cancer screening [ 42 ]. Unlike these methods analyzed from the perspective of genetic testing and cytology, colposcopy is more intuitive to observe and diagnose from the morphology.…”

Section: Limitation and Discussionmentioning

confidence: 99%

Cervical Lesion Classification Method Based on Cross-Validation Decision Fusion Method of Vision Transformer and DenseNet

Wang

Liu

et al. 2022

Journal of Healthcare Engineering

View full text Add to dashboard Cite

Objective. In order to better adapt to clinical applications, this paper proposes a cross-validation decision-making fusion method of Vision Transformer and DenseNet161. Methods. The dataset is the most critical acetic acid image for clinical diagnosis, and the SR areas are processed by a specific method. Then, the Vision Transformer and DenseNet161 models are trained by the fivefold cross-validation method, and the fivefold prediction results corresponding to the two models are fused by different weights. Finally, the five fused results are averaged to obtain the category with the highest probability. Results. The results show that the fusion method in this paper reaches an accuracy rate of 68% for the four classifications of cervical lesions. Conclusions. It is more suitable for clinical environments, effectively reducing the missed detection rate and ensuring the life and health of patients.

show abstract

Section: Limitation and Discussionmentioning

confidence: 99%

Cervical Lesion Classification Method Based on Cross-Validation Decision Fusion Method of Vision Transformer and DenseNet

Wang

Liu

et al. 2022

Journal of Healthcare Engineering

View full text Add to dashboard Cite

show abstract

“…No Brasil, a implantação de um modelo de rastreamento organizado poderá viabilizar o uso de testes de HPV e o aumento do intervalo de trienal para quinquenal e da faixa etária de início de 25 para 30 anos 45,46 . O estudo realizado por Teixeira et al 47 demostrou que a organização do rastreamento do câncer do colo do útero usando testes de DNA-HPV resultaria em impacto imediato na detecção de casos em estágio inicial.…”

Section: Figuraunclassified

Avaliação das ações de controle do câncer de colo do útero no Brasil e regiões a partir dos dados registrados no Sistema Único de Saúde

et al. 2022

View full text Add to dashboard Cite

Este estudo teve como objetivo analisar a realização de exames de rastreamento e diagnóstico para o câncer de colo do útero entre mulheres de 25 e 64 anos, bem como o atraso para o início do tratamento no Brasil e suas regiões geográficas no período de 2013 a 2020. As informações sobre os procedimentos e as estimativas populacionais foram obtidas nos sistemas de informações do Sistema Único de Saúde (SUS) e da Agência Nacional de Saúde Suplementar (ANS). Foram calculados indicadores de cobertura do exame de Papanicolau, os percentuais de exames citopatológicos e histopatológicos alterados, e o percentual de mulheres com diagnóstico de câncer do colo do útero tratadas com mais de 60 dias. Houve grande variação na cobertura do exame de Papanicolau entre as regiões brasileiras com tendência de declínio a partir de 2013, agudizada de 2019 para 2020. O número registrado de exames citopatológicos alterados foi 40% inferior ao estimado e a diferença entre o número registrado de diagnósticos de câncer e o estimado menor que 50%. O percentual das mulheres com diagnóstico de câncer invasivo do colo do útero que iniciaram o tratamento após 60 dias variou entre 50% na Região Sul a 70% na Região Norte, com diminuição a partir de 2018. Em 2020, houve retração do número de exames de rastreamento e de seguimento com diminuição da proporção de mulheres com atraso para o início do tratamento nas regiões Norte, Sudeste e Sul. A queda na cobertura do rastreamento e o seguimento inadequado de mulheres com resultados alterados indicam a necessidade de aprimorar as estratégias de detecção precoce da doença e estabelecer mecanismos de avaliação e monitoramento constante das ações.

show abstract

“…Although HPV detection tests have not yet been incorporated into SUS, recommendations to guide professionals working in scenarios in which these tests are available have already been published, so they can be used based on scientific evidence and according to best practices (32). Additionally, studies investigating the molecular approach shift in CC screening in the Brazilian context have been conducted and published (33)(34)(35)(36)(37).…”

Section: Cervical Cancer Screeningmentioning

confidence: 99%

Cervical cancer screening, treatment and prophylaxis in Brazil: Current and future perspectives for cervical cancer elimination

et al. 2022

View full text Add to dashboard Cite

As a middle-income country, Brazil has one of the largest public health systems worldwide, which deals with free and universal access to health care. Regarding cervical cancer, the country possesses a large infrastructure for the screening of premalignant and malignant lesions, but yet based on old technology, having Papanicolaou as the major screening method, followed by colposcopy and treatment. Also, large disparities in access are present, which makes effectiveness of screening and treatment in different regions of the country highly unequal. In this review, we describe and evaluate the current screening, treatment and prophylactic (HPV vaccination) strategies to combat cervical cancer in Brazil, and discuss potential incorporation of more recent technologies in these areas in the country to pave its way toward cervical cancer elimination.

show abstract

Organization of cervical cancer screening with DNA–HPV testing impact on early–stage cancer detection: a population–based demonstration study in a Brazilian city

Cited by 17 publications

References 21 publications

Cervical Lesion Classification Method Based on Cross-Validation Decision Fusion Method of Vision Transformer and DenseNet

Cervical Lesion Classification Method Based on Cross-Validation Decision Fusion Method of Vision Transformer and DenseNet

Avaliação das ações de controle do câncer de colo do útero no Brasil e regiões a partir dos dados registrados no Sistema Único de Saúde

Cervical cancer screening, treatment and prophylaxis in Brazil: Current and future perspectives for cervical cancer elimination

Contact Info

Product

Resources

About