Organic Synthesis Based on Cyclodextrins Template Method

Abstract

The organic synthesis based on cyclodextrin template method is reviewed initially by using the "template" concept.These organic synthesis reactions are divided into two main types: one type is based on cyclodextrin "static" template which includes the primary, secondary faces and the cavity. The reactions based on the primary and secondary faces mainly show that the template can control the stereo-structure. While the reactions based on the cavity are mainly using the size and chiral properties of the cavity to do the chemical, regio-and stereo-selectivity, showing that the template can carry out information transfer. The other type is based on cyclodextrin "dynamic" template including the bridge-linked cyclodextrin dimmers with variable conformations and the assemblies prepared by the cyclodextrin derivatives and inclusion complexes. These dynamic templates themselves can be adjusted.

Synthesis, Structures of Macrocyclic Compounds and Study on Recognition for La(Ⅲ) Ion

“…在众多的大环化合物中, 含氮、 氧等杂原子的大环 配体具有环腔大小可控、环内配位供体原子(氮、氧原 子)数目可变 [4,5] , 特别是大环结构刚、柔性易于调整, 使 得类似大环在同金属离子进行配位键合作用时, 一方面 因为环缘上的氮、氧原子配位取向灵活多变, 易于得到 新颖的配合物结构 [6,7] ; 另一方面, 有利于提高其与金属 离子配位作用的选择性 [8] . 因此设计、合成含氮、氧等 杂原子的有机大环, 并开展其与金属离子之间的配位化 学研究一直受到人们的普遍青睐 [9] .…”