2018
DOI: 10.1021/acs.langmuir.8b01313
|View full text |Cite
|
Sign up to set email alerts
|

Organic Semiconductor Laser Platform for the Detection of DNA by AgNP Plasmonic Enhancement

Abstract: Organic semiconductor lasers are a sensitive biosensing platform that respond to specific biomolecule binding events. So far, such biosensors have utilized protein-based interactions for surface functionalization but a nucleic acid-based strategy would considerably widen their utility as a general biodiagnostic platform. This manuscript reports two important advances for DNA-based sensing using an organic semiconductor (OS) distributed feedback (DFB) laser. First, the immobilization of alkyne-tagged 12/18-mer … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
8
0

Year Published

2019
2019
2024
2024

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 9 publications
(8 citation statements)
references
References 54 publications
0
8
0
Order By: Relevance
“…The analysis was comparable with that from the literature. 64 General procedure D: Deprotection of the trimethylsilane group of (bromooligofluorenyl)trimethylsilanes (8) 41 To a solution of (bromooligofluorenyl)trimethylsilane (TMS-Fn-Br) (1 eq) in dichloromethane (16 mL per gram), CF3COOH (15 eq) was added and the mixture stirred at room temperature for 2 h. Basic work up was carried out with water (2 times), saturated NaHCO3 solution (2 times) and final washing with water. The organic fraction was dried over anhydrous MgSO4 and filtered through a silica plug to remove polar by-products and crystallized from acetone to yield the product.…”
Section: B)mentioning
confidence: 99%
See 2 more Smart Citations
“…The analysis was comparable with that from the literature. 64 General procedure D: Deprotection of the trimethylsilane group of (bromooligofluorenyl)trimethylsilanes (8) 41 To a solution of (bromooligofluorenyl)trimethylsilane (TMS-Fn-Br) (1 eq) in dichloromethane (16 mL per gram), CF3COOH (15 eq) was added and the mixture stirred at room temperature for 2 h. Basic work up was carried out with water (2 times), saturated NaHCO3 solution (2 times) and final washing with water. The organic fraction was dried over anhydrous MgSO4 and filtered through a silica plug to remove polar by-products and crystallized from acetone to yield the product.…”
Section: B)mentioning
confidence: 99%
“…The organic fraction was dried over anhydrous MgSO4 and filtered through a silica plug to remove polar by-products and crystallized from acetone to yield the product. 7-Bromo-9,9,9',9',9'',9'',9''',9'''-octaoctyl-2,2':7',2'':7''',2'''-quaterfluorene (8) Using the general procedure D, the quantities used were: (7'''-bromo-9,9,9',9',9'',9'',9''',9'''-octaoctyl-2,2':7',2'':7'',2'''-quaterfluoren-7-yl)trimethylsilane (7 O) (2.96 g, 1.74•10 -3 mol), dichloromethane (56 mL), CF3COOH (1.8 mL). The product was obtained as a white crystalline solid (2.74 g, 1.68•10 -3 mol, 96%).…”
Section: B)mentioning
confidence: 99%
See 1 more Smart Citation
“…Strictly speaking, the above two DFB laser examples do not fall into the biolaser definition, as they act merely like passive label‐free optical biosensors. Very recently, McConnel et al developed a sequence‐selective detection of analytes (oligodeoxyribonucleotide, ODN) using a hybrid DNA/organic laser in conjunction with Ag nanoparticles . As binding occurs, the nanoparticles increase the optical losses of the laser mode through plasmonic scattering and absorption, which in turn results in an increased lasing threshold.…”
Section: Biological and Biomedical Sensingmentioning
confidence: 99%
“…In the past decade, dyes, quantum dots, quantum wells, nanowires, rare‐earth materials, fluorescent proteins, fluorescent product resulting from enzyme–substrate reaction, and other naturally fluorescent biomaterials have been used to participate actively in lasing action . Biolasers have been employed in the detection of various bioactivities at the molecular, cellular, and tissue levels . Recently, their applications in cell tracking, labeling/probes, implantable devices, cell/tissue imaging start to emerge.…”
Section: Introductionmentioning
confidence: 99%