Organic Selenium Compounds. Part I: Synthesis and Application of Some New Diaryl-Selenides and Selenones Containing Amino Acid Moieties

Selenium containing Heterocycles: Part 1. Synthesis of Some New Substituted Pyrido[3′,2′:4,5]selenolo[3,2-d]pyrimidines and Related Fused Tetracyclic Systems

“…IR: ν max 3050 cm -1 (CH-aromatic). 1 3-Amino-3,4-dihydro-4-imino-7,9-dimethylpyrido [3',2':4,5]selenolo [3,2-d]pyrimidine (22) The iminoether 21 (3.06 g, 10 mmol) was suspended in dioxan (10 ml), hydrazine hydrate (99%, 2 ml) was added, the reaction mixture was stirred at room temperature for 3 h. The solid product that formed was collected and recrystallised from dioxan as white crystals (2.54 g, 87%), m.p. >300°C.…”

“…[9][10][11][12][13][14] Also organic selenium compounds have proven to be an important class of biologically active compounds as antioxidants, 15 antibacterial agents 16 and catalysts. 17 Considering the foregoing benefits, and in continuation of our efforts in the preparation of new heterocyclic systems containing selenium and/or sulfur moieties, [18][19][20][21][22][23][24] we aimed to combine the selenophene ring with the pyridine nucleus giving selenolo [2,3-b]pyridine derivatives in the hope that members of this series may find interesting biological applications.…”

The synthesis of thiols, selenols, sulfides, selenides, sulfoxides, selenoxides, sulfones and selenones

“…The chemistry of selenones continues to receive little attention although a recent study has detailed the preparation of diaryl selenones 38, and their antibacterial properties have been evaluated. 176 4.1 Oxidation of sulfides and sulfoxides. The oxidation of diaryl and dialkyl sulfoxides to the corresponding sulfones using hydrogen peroxide and methyltrioxorhenium as catalyst has been the subject of a kinetic investigation.…”

Syntheses of New Unsymmetrical and Symmetrical Diarylsulphides and Diarylsulphones Containing Thiazolinyl and Thiazolidinonyl Moieties Using 4,4'-Diacetyldiphenylsulphide

“…During the last three decades considerable work from the laboratory of M.A. Abbady et al has been published describing the synthesis of new diaryl sulphides, diaryl sulphones, diaryl selenides and diaryl selenones [ 18 , 19 ] containing varied additional moieties, as well as their evaluation as potential pharmaceuticals.…”