Over the last 15 years a striking pattern of diversification has been documented in the fossil record of benthic marine invertebrates. Higher taxa (orders) tend to originate onshore, diversify offshore, and retreat into deepwater environments. Previous studies attribute this macroevolutionary pattern to a variety of causes, foremost among them the role of nearshore disturbance in providing opportunities for the evolution of novel forms accorded ordinal rank. Our analysis of the post-Paleozoic record of ordinal first appearances indicates that the onshore preference of ordinal origination occurred only in the Mesozoic prior to the Turonian stage of the Cretaceous, a period characterized by relatively frequent anoxic͞dysoxic bottom conditions in deeper marine environments. Later, in the Cretaceous and Cenozoic, ordinal origination of benthic organisms did not occur exclusively, or even preferentially, in onshore environments. This change in environmental pattern of ordinal origination roughly correlates with Late Cretaceous: (i) decline in anoxia͞dysoxia in offshore benthic environments; (ii) extinction of faunas associated with dysoxic conditions; (iii) increase in bioturbation with the expansion of deep burrowing forms into offshore environments; and (iv) offshore expansion of bryozoan diversity. We also advance a separate argument that the Cenomanian͞Turonian and latest Paleocene global events eliminated much of the deep-water benthos. This requires a more recent origin of modern vent and deep-sea faunas, from shallower water refugia, than the Paleozoic or early Mesozoic origin of these faunas suggested by other workers.An onshore to offshore evolutionary pattern is evident in benthic marine invertebrate clades of the Paleozoic (1, 2) and post-Paleozoic (3-7) age. Ordinal rank taxa are observed to originate onshore, diversify offshore, and eventually relinquish nearshore habitat. This pattern has been attributed to a number of factors (5), the most clearly articulated of which invokes higher disturbance in shallow marine environments as a mechanism that eliminates niche incumbents, permitting the evolution of novel attributes subsequently recognized as new, ordinal rank, higher taxa (8). Expansion across the shelf to deeper offshore habitats then accompanies diversification of the clade (3-6). Explanations advanced for the subsequent offshore retreat of taxonomic groups include the evolution of new predators (9) and more effective competitors (10) in the nearshore environment. Thus, the nearshore is thought of as a source of evolutionary novelty resulting from disturbance, and subsidiary aspects of the pattern, such as offshore retreat, are thought of as responses to ecological interaction associated with the appearance of evolutionary novelty in the nearshore.In this paper we argue (i) that a component of the postPaleozoic onshore͞offshore evolutionary pattern (3-7) resulted from the preferential influence of anoxic͞dysoxic bottom conditions (a͞dbc) on offshore faunas; (ii) that a͞dbc were prevalent in...