Organic photosensitizers for antimicrobial phototherapy

Nguyen, Van‐Nghia; Zhao, Zheng; Tang, Ben Zhong; Yoon, Juyoung

doi:10.1039/d1cs00647a

Cited by 176 publications

(127 citation statements)

References 79 publications

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“…Consequently, coating implants with antibiotic eluting materials seems to be one of the best options to prevent the infection and formation of biofilms [ [3] , [4] , [5] , [6] ]. One mechanism devised to overcome this challenge is the painting of surfaces of devices which can be said to be a traditional means [ [7] , [8] , [9] ]. However, this method may not be safe and reliable since any minimal scratch can still provide a surface for the bacteria to thrive.…”

Section: Introductionmentioning

confidence: 99%

Polydopamine, harness of the antibacterial potentials-A review

Obeng

Sun

et al. 2022

Materials Today Bio

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Section: Introductionmentioning

confidence: 99%

Polydopamine, harness of the antibacterial potentials-A review

Obeng

Sun

et al. 2022

Materials Today Bio

Self Cite

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“…The photosensitizers can be activated under a light source to generate reactive oxygen species (ROS) to kill cancer cells. In particular, PDT can avoid systemic toxicity with fewer side effects than chemotherapy due to its high spatiotemporal selectivity ( Li et al, 2018 ; Zhang et al, 2019 ; Nguyen et al, 2022 ). To achieve synergistic therapeutic effects with different mechanisms for eliminating breast cancer, combination therapies involving both PDT and PTT have been developed ( Su et al, 2015 ; Lee et al, 2022 ; Xu et al, 2022 ).…”

Section: Photothermal Therapy On Bc Metastasismentioning

confidence: 99%

Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer

Sun

Zhao

et al. 2022

Front. Chem.

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Breast cancer (BC) is one of the most common cancers in women worldwide; however, the successful treatment of BC, especially triple-negative breast cancer (TNBC), remains a significant clinical challenge. Recently, photothermal therapy (PTT), which involves the generation of heat under irradiation to achieve photothermal ablation of BC with minimal invasiveness and outstanding spatial–temporal selectivity, has been demonstrated as a novel therapy that can overcome the drawbacks of chemotherapy or surgery. Significantly, when combining PTT with chemotherapy and/or photodynamic therapy, an enhanced synergistic therapeutic effect can be achieved in both primary and metastatic BC tumors. Thus, this review discusses the recent developments in nanotechnology-based photothermal therapy for the treatment of BC and its metastasis to provide potential strategies for future BC treatment.

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“…[8][9][10] Photodynamic inactivation (PDI) is a noninvasive therapeutic strategy for the combat of microbe infections. 11,12 In PDI, photosensitizers (PSs) and light illumination are utilized to generate cytotoxic reactive oxygen species (ROS), which can cause oxidative damage to membrane lipids, nucleic acids, and proteins and induce the death of pathogens. With the superiority of limited antibiotic resistance, low systemic toxicity, and high specificity, PDI has attracted increasing attention.…”

Section: Introductionmentioning

confidence: 99%