Organic photoelectrochemical transistor detection of tear lysozyme

Abstract

Rational utilization of rich interplay between light and materials taking place in organic electrochemical transistor (OECT) is emerging and gaining more interest by the scientific community. Light modulation is expected...

Duplex-Specific Nuclease-Enabled Target Recycling on Semiconducting Metal–Organic Framework Heterojunctions for Energy-Transfer-Based Organic Photoelectrochemical Transistor miRNA Biosensing

“…Essentially, the OPECT operation follows the PEC biochemical reactions at the solid/electrolyte interface and the volumetric ionic injection-dependent modulation of the channel conductivity in OECTs. , Such a rationale creates an enormous opportunity for exploring various biochemical reactions to photoelectrochemically influence the potential distribution across channel/electrolyte and gate/electrolyte interfaces and thus manipulate OECT responses as reflected by channel currents, which, nevertheless, has hitherto been studied by only a few researchers . Bearing in mind the potential of semiconductor MOF heterojunctions, we reason that the exploitation of such materials may advance the nascent OPECT technology.…”

Alkaline Phosphatase-Mediated Bioetching of CoOOH/BiVO4 for Signal-On Organic Photoelectrochemical Transistor Bioanalysis

“…The synergy between PEC bioanalysis and transistor operation has been emerging as an innovative method to this end. , Especially, the nascent organic photoelectrochemical transistor (OPECT) bioanalysis interfacing PEC bioanalysis with an organic electrochemical transistor (OECT) − has been principally proved as a feasible approach for probing biological events with essential amplification capability. , In the OPECT, biorelated manipulation of the light-harvesting gates could sensitively modulate the device behaviors as monitored by the amplified channel current ( I d ), underpinning the interconnectivity among the bioworld, PEC transduction, and transistor amplification. , Rational usage of the rich light–matter–bio interplay occurring at this forefront further makes possible exquisite OPECT operation of a light-sustained, bio-dependent, zero-bias-gated, and even self-powered fashion. , Albeit its obvious advantages and potential, the study in this arena is just in its infancy and further establishment of advanced OPECT interrogation of biological systems is highly anticipated.…”

“…20,21 In the OPECT, biorelated manipulation of the light-harvesting gates could sensitively modulate the device behaviors as monitored by the amplified channel current (I d ), underpinning the interconnectivity among the bioworld, PEC transduction, and transistor amplification. 22,23 Rational usage of the rich light−matter−bio interplay occurring at this forefront further makes possible exquisite OPECT operation of a lightsustained, bio-dependent, zero-bias-gated, and even selfpowered fashion. 24,25 Albeit its obvious advantages and potential, the study in this arena is just in its infancy and further establishment of advanced OPECT interrogation of biological systems is highly anticipated.…”

Polymer dots synergized with a NiO hole transporting layer and poly(amido amine) dendrimer: toward sensitive photocathodic detection of tyrosinase level in serum

“…Photoelectrochemical (PEC) bioanalysis is a rapidly developing methodology for sensitive biomolecule detection with a fast response, low background and high sensitivity. 11–16 In comparison with the well-studied photoanodic bioanalysis, 17–26 serious consideration of p-type light-harvesting materials for photocathodic bioanalysis is relatively recent. 27–31 Nevertheless, because of their desirable properties such as higher stability than the anodic system and superior anti-interference capability against reductive substances in actual biological samples, exploration in this direction is gaining strong momentum.…”