Organic nanomaterials for near-infrared light-triggered photothermal/thermodynamic combination therapy

Zhou, Wen; Du, Mingzhi; Wang, Jinghui; Zhang, Xuheng; Liang, Tingting; Xie, Chen; Fan, Quli

doi:10.1016/j.dyepig.2022.110499

Cited by 7 publications

(4 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thermal effects have been widely applied in clinical settings for cancer treatments based on different nanomaterials. [311][312][313] Thermodynamic therapy (TDT) utilizes thermal effects to generate radicals for tumor inhibition, which is different from other therapeutic modalities with a direct tumor-ablating ability. This process can be activated using various stimuli, including light irradiation, 314,315 magnetic field induction, 316,317 and microwave (MW) stimulation.…”

Section: Review Articlementioning

confidence: 99%

“…15a). 311,313 Wang et al prepared Bi 13 S 18 I 2 nanorods (NRs) to perform photothermal conversion in P-TDT with a high inhibition rate of 97.2% towards tumor tissues. 320 The insertion of a third biocompatible agent of iodine enabled Bi 13 S 18 I 2 NRs with an enhanced pyrocatalytic conversion efficiency and the ability to produce enough ROS to inhibit tumor progression.…”

Section: Review Articlementioning

confidence: 99%

See 1 more Smart Citation

Reactive X (where X = O, N, S, C, Cl, Br, and I) species nanomedicine

Wang,

Mao,

Song

et al. 2023

Chem. Soc. Rev.

View full text Add to dashboard Cite

show abstract

Section: Review Articlementioning

confidence: 99%

Section: Review Articlementioning

confidence: 99%

Reactive X (where X = O, N, S, C, Cl, Br, and I) species nanomedicine

Wang,

Mao,

Song

et al. 2023

Chem. Soc. Rev.

View full text Add to dashboard Cite

show abstract

“…PTAs are generally nanomaterials, which can be divided into organic, inorganic, and organic–inorganic composite nanomaterials according to their chemical composition. − The most commonly used organic PTAs are indocyanine green (ICG) and its analogues, as well as conductive polymers. In 1995, researchers began a series of studies on the tumor ablative ability of ICG, from being discovered for tumor ablation, to in situ injection for tumor treatment, , and to the development of targeted tumor treatment by preparing ICG-based nanoparticles .…”

Section: Photothermal Composite Scaffoldsmentioning

confidence: 99%

Advances in the Application of Photothermal Composite Scaffolds for Osteosarcoma Ablation and Bone Regeneration

Chen,

Yang,

et al. 2023

ACS Omega

View full text Add to dashboard Cite

Photothermal therapy is a promising approach to cancer treatment. The energy generated by the photothermal effect can effectively inhibit the growth of cancer cells without harming normal tissues, while the right amount of heat can also promote cell proliferation and accelerate tissue regeneration. Various nanomaterials have recently been used as photothermal agents (PTAs). The photothermal composite scaffolds can be obtained by introducing PTAs into bone tissue engineering (BTE) scaffolds, which produces a photothermal effect that can be used to ablate bone cancer with subsequent further use of the scaffold as a support to repair the bone defects created by ablation of osteosarcoma. Osteosarcoma is the most common among primary bone malignancies. However, a review of the efficacy of different types of photothermal composite scaffolds in osteosarcoma is lacking. This article first introduces the common PTAs, BTE materials, and preparation methods and then systematically summarizes the development of photothermal composite scaffolds. It would provide a useful reference for the combination of tumor therapy and tissue engineering in bone tumor-related diseases and complex diseases. It will also be valuable for advancing the clinical applications of photothermal composite scaffolds.

show abstract

“…Cancer remains a significant global health issue, and extensive efforts and research have been devoted to understanding cancer and advancing its treatment [1,2]. To date, various treatment methods have been developed, with approaches such as chemotherapy (CHT) [3], photodynamic therapy (PDT) [4][5][6][7], photothermal therapy (PTT) [8][9][10][11][12], immunotherapy (IMT) [13][14][15][16], cancer starvation therapy (CST) [17][18][19][20][21], thermodynamic therapy (TDT) [22][23][24][25][26][27], chemodynamic therapy (CDT) [28][29][30][31][32][33], magnetothermal therapy (MTT) [34][35][36][37][38], and radiotherapy (RT) [39][40][41]. However, each treatment method has its own limitations and disadvantages.…”

Section: Introductionmentioning

confidence: 99%

Advancing Cancer Treatment: Enhanced Combination Therapy through Functionalized Porous Nanoparticles

Kim,

Park

2024

Biomedicines

View full text Add to dashboard Cite

Cancer remains a major global health challenge, necessitating the development of innovative treatment strategies. This review focuses on the functionalization of porous nanoparticles for combination therapy, a promising approach to enhance cancer treatment efficacy while mitigating the limitations associated with conventional methods. Combination therapy, integrating multiple treatment modalities such as chemotherapy, phototherapy, immunotherapy, and others, has emerged as an effective strategy to address the shortcomings of individual treatments. The unique properties of mesoporous silica nanoparticles (MSN) and other porous materials, like nanoparticles coated with mesoporous silica (NP@MS), metal–organic frameworks (MOF), mesoporous platinum nanoparticles (mesoPt), and carbon dots (CDs), are being explored for drug solubility, bioavailability, targeted delivery, and controlled drug release. Recent advancements in the functionalization of mesoporous nanoparticles with ligands, biomaterials, and polymers are reviewed here, highlighting their role in enhancing the efficacy of combination therapy. Various research has demonstrated the effectiveness of these nanoparticles in co-delivering drugs and photosensitizers, achieving targeted delivery, and responding to multiple stimuli for controlled drug release. This review introduces the synthesis and functionalization methods of these porous nanoparticles, along with their applications in combination therapy.

show abstract

Organic nanomaterials for near-infrared light-triggered photothermal/thermodynamic combination therapy

Cited by 7 publications

References 66 publications

Reactive X (where X = O, N, S, C, Cl, Br, and I) species nanomedicine

Reactive X (where X = O, N, S, C, Cl, Br, and I) species nanomedicine

Advances in the Application of Photothermal Composite Scaffolds for Osteosarcoma Ablation and Bone Regeneration

Advancing Cancer Treatment: Enhanced Combination Therapy through Functionalized Porous Nanoparticles

Contact Info

Product

Resources

About