Organic electrochemical transistor based biosensor for detecting marine diatoms in seawater medium

Liao, Jianjun; Lin, Shiwei; Li, Kai; Yang, Yue; Zhang, RuiRui; Du, Wencai; Li, Xiaogan

doi:10.1016/j.snb.2014.07.052

Cited by 23 publications

(19 citation statements)

References 37 publications

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“…The mechanism of sensing is as described above; owing to its charge, the DNA affects the capacitance at the interface between gate and electrolyte, and thus shifts V g,eff. A similar mechanism was also shown by Liao et al, for the detection of diatoms, a type of algae found in sea water . An interesting observation was that PEDOT:PSS appeared to promote diatom growth when compared with simple glass slides.…”

Section: Applications In Biologysupporting

confidence: 76%

The organic electrochemical transistor for biological applications

Strakosas

Bongo

Owens

2015

J of Applied Polymer Sci

285

262

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The rising field of bioelectronics, which couples the realms of electronics and biology, holds huge potential for the development of novel biomedical devices for therapeutics and diagnostics. Organic electronic devices are particularly promising; the use of robust organic electronic materials provides an ideal biointerface due to their reported biocompatibility, and mechanical matching between the sensor element and the biological environment, are amongst the advantages unique to this class of materials. One promising device emerging from this field is the organic electrochemical transistor (OECT). Arguably, the most important feature of an OECT is that it provides local amplification and as such can be used as a high fidelity transducer of biological events. Additionally, the OECT combines properties and characteristics that can be tuned for a wide spectrum of biological applications. Here, we frame the development of the OECT with respect to its underlying optimization for a variety of different applications, including ion sensing, enzymatic sensing, and electrophysiology. These applications have allowed the development of OECTs to sense local ionic/biomolecular and single cell activity, as well characterization of tissue and even monitoring of function of whole organs. The body of work reviewed here demonstrates that the OECT is an extremely versatile device that emerges as an important player for therapeutics and diagnostics.

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Section: Applications In Biologysupporting

confidence: 76%

The organic electrochemical transistor for biological applications

Strakosas

Bongo

Owens

2015

J of Applied Polymer Sci

285

262

View full text Add to dashboard Cite

show abstract

“…Åsberg and Inganäs prepared 3‐D enzyme electrode containing horseradish peroxidase (HRP) for the estimation of H 2 O 2 , and the drop‐coated PEDOT–PSS film was utilized as electro‐active hydrogel matrix in a biosensor or bio‐molecule enhanced electrode with osmium as mediator. Noguer et al designed PEDOT–PSS screen‐printed biosensor based on tyrosinase or acetylcholinesterase for the detection of chlorpyrifos‐oxon and phenolic compounds, respectively . Dutse et al drop‐coated PEDOT–PSS‐AgNPs onto gold electrode for fabricating DNA‐based biosensor, and ganoderma boninense was successfully detected using ruthenium complex [Ru(phen) 2 (qtpy)] 2+ as effective hybridization indicator .…”

Section: Pedot–pss Film Electrode For Sensing Applicationmentioning

confidence: 99%

“… Schematic diagram for the device structure of PEDOT:PSS‐based organic electrochemical transistor for sensing glucose and marine diatoms (a) side view; (b) top view; and (c) chemical structures of PEDOT and PSS …”

Section: Pedot–pss Film Electrode For Sensing Applicationmentioning

confidence: 99%

Scientific Importance of Water‐Processable PEDOT–PSS and Preparation, Challenge and New Application in Sensors of Its Film Electrode: A Review

Wen

2017

J. Polym. Sci. Part A: Polym. Chem.

270

188

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In this review, PEDOT-PSS is mainly a commercially available PEDOT-PSS, which is a water-dispersible form of the intrinsically conducting PEDOT doped with the watersoluble PSS, including its derivatives, copolymers, analogs (PEDOT:PSSs), even their composites via the chemical or physical modification toward the structure of PEDOT and/or PSS. First, we will focus on discussing the scientific importance of PEDOT-PSS in conjunction with its extraordinary properties and broad multidisciplinary applications in organic/polymeric electronics and optoelectronics from the viewpoint of the historical development and the promising application of representative ECPs. Subsequently, versatile film-forming techniques for the preparation of PEDOT-PSS film electrode were described in details, including common coating approaches and printing techniques, and many emerging preparative methods were mentioned. Then challenges (e.g., conductivity, stability in Water, adhesion to substrate electrode) of PEDOT-

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“…[8] Recently, a special attention has been paid to a peculiar class of transistors, i.e., the organic electro-chemical transistors (OECTs). Although the main interest on OECTs relies on their unprecedented performances as sensors of a large variety of (bio) analytes (e.g., metallic cations, [9] micrometer-sized biomolecules, [10] DNA, [11] bacteria, [12] or marine diatoms [13] ), their function covers a wide set of applications. For instance, the use of semi-biotic interfaces in OECTs architectures has allowed the implementation of multifunctional [14] and synaptic-like memory [15] devices.…”

Section: Introductionmentioning

confidence: 99%