Organ procurement and transplantation during the COVID-19 pandemic

Loupy, Alexandre; Aubert, Olivier; Reese, Peter P.; Bastien, Olivier; Bayer, Florian; Jacquelinet, Christian

doi:10.1016/s0140-6736(20)31040-0

Cited by 249 publications

(291 citation statements)

References 3 publications

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“…10 España Disminución del 84% en donación y trasplante, suspensión temporal de trasplantes con donante vivo. 11,12 Estados Unidos Disminución del 51,1% en trasplantes totales y 71,8% en trasplantes con donante vivo 13,14 Francia Disminución del 90,6% de trasplantes 14…”

Section: Italiaunclassified

Donación y trasplante de órganos en medio de la pandemia COVID-19: Consecuencias y retos para un país emergente

Castañeda-Millán

Pardo-Acuña

Cortés-Páez

et al. 2020

Revista Urología Colombiana / Colombian Urology Journal

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ResumenLa pandemia del SARS-CoV 2 es uno de los eventos en salud pública más relevantes de los últimos años, sus efectos se han traducido en millones de casos de contagios, en más de 430.000 fallecimientos y en un aumento en la necesidad de camas de cuidados intensivos alrededor del mundo. En ese contexto, se ha presentado una reducción significativa de la actividad de donación y trasplantes en varios países, y Colombia no ha sido ajena a ese fenómeno. El presente artículo, pretende dar al lector una perspectiva del estado actual de la donación y trasplantes en el mundo y en Colombia, así como plantear algunos retos que genera la pandemia del SARS-CoV 2 para la ejecución segura del proceso de donación y trasplantes en países con recursos humanos, financieros y de infraestructura limitados.

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Section: Italiaunclassified

Donación y trasplante de órganos en medio de la pandemia COVID-19: Consecuencias y retos para un país emergente

Castañeda-Millán

Pardo-Acuña

Cortés-Páez

et al. 2020

Revista Urología Colombiana / Colombian Urology Journal

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“…It has been reported that transplant patients acquiring coronavirus disease 2019 (COVID-19) have increased mortality, with more atypical presentations and longer duration of virus shedding[ 2 , 3 ]. Loupy et al[ 4 ] has reported a strong association between rising coronavirus infections and a marked reduction in the overall number of solid-organ transplantation, even in geographic regions with low infection prevalence. All of these could be devastating for patients awaiting organ transplantation.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 pandemic: Building organisational flexibility to scale transplant programs

Gopal

Papalois

2020

WJT

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The prevailing coronavirus disease 2019 pandemic has challenged our lives in an unprecedented manner. The pandemic has had a significant impact on transplantation worldwide. The logistics of travel restrictions, stretching of available resources, unclear risk of infection in immunosuppressed transplant recipients, and evolving guidelines on testing and transplantation are some of the factors that have unfavourably influenced transplant activity. We must begin to build organisational flexibility in order to restart transplantation so that we can be mindful stewards of organ donation and sincere advocates for our patients. Building a culture of honesty and transparency (with patients, families, colleagues, societies, and authorities), keeping the channels of communication open, working in collaboration with others (at local, regional, national, and international levels), and not restarting without rethinking and appraising all elements of our practice, are the main underlying principles to increase the flexibility.

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“…Second, immunosuppressed KT recipients may have prolonged viral shedding and transmissibility, potentially posing a greater risk to public health [8,9]. Third, there is concern that hospitals will not have the resources to safely perform KT and provide the necessary post-operative care [10]. These changes are not without consequences; postponing KT can lead to a higher waitlist mortality, and diverting resources away from transplant recipients may worsen post-operative outcomes [11,12].…”

Section: Introductionmentioning

confidence: 99%

Effects of COVID19 Pandemic on Pediatric Kidney Transplant in the United States

Charnaya

Chiang

Wang

et al. 2020

Preprint

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In March 2020, COVID-19 infections began to rise exponentially in the United States, placing substantial burden on the healthcare system. As a result, there was a rapid change in transplant practices and policies, with cessation of most procedures. Our goal was to understand changes to pediatric kidney transplantation (KT) at the national level during the COVID-19 epidemic. Using SRTR data, we examined changes in pediatric waitlist registration, waitlist removal or inactivation, and deceased donor and living donor (DDKT/LDKT) events during the start of the disease transmission in the United States compared to the same time the previous year. We saw an initial decrease in DDKT and LDKT by 47% and 82% compared to expected events and then a continual increase, with numbers reaching expected pre-pandemic levels by May 2020. In the early phase of the pandemic, waitlist inactivation and removals due to death or deteriorating condition rose above expected values by 152% and 189%, respectively. There was a statistically significant decrease in new waitlist additions (IRR 0.49 0.65 0.85) and LDKT (IRR 0.17 0.38 0.84) in states with high vs low COVID activity. Transplant recipients during the pandemic were more likely to have received a DDKT, but had similar cPRA, waitlist time and cause of ESRD as before the pandemic. The COVID-19 pandemic initially reduced access to kidney transplantation among pediatric patients in the United States, but has not had a sustained effect.

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Organ procurement and transplantation during the COVID-19 pandemic

Cited by 249 publications

References 3 publications

Donación y trasplante de órganos en medio de la pandemia COVID-19: Consecuencias y retos para un país emergente

Donación y trasplante de órganos en medio de la pandemia COVID-19: Consecuencias y retos para un país emergente

COVID-19 pandemic: Building organisational flexibility to scale transplant programs

Effects of COVID19 Pandemic on Pediatric Kidney Transplant in the United States

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