Direct-gap photoluminescence (PL) at the wavelength around 1.55 μm from Ge epitaxial layers on Si is studied toward Ge lasers in Si photonics. Comparing the PL intensities under two different wavelengths of excitation lasers, non-radiative interface recombination velocities are estimated to be as large as 105 cm s−1 at Ge/Si and Ge/air interfaces, whereas that at the Ge/GeO2 interface is estimated to be as small as 103–104 cm s−1, which is required for the threshold current density in Ge lasers as low as 10 kA cm−2. In order to remove the effect of defect-rich Ge/Si hetero-interfaces with a high recombination velocity, a wet chemical treatment in a CH3COOH/HNO3/HF/I2 solution is examined. A preferential etching of Ge at Ge/Si interfaces leads to an enhancement of the PL peak intensity by 83 times. A suppression of non-radiative recombination at the Ge/Si interface should contribute to this enhancement, and such a suppression plays a critical role for Ge lasers.