Orbital myositis in systemic lupus erythematosus: a case-based review

Venetsanopoulou, Aliki I.; Pieta, Antigone; Tziortzioti, Zoi; Anastasia, Zikou K; Aa, Drosos

doi:10.1007/s00296-022-05114-3

Cited by 4 publications

(2 citation statements)

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“…Orbital myositis in SLE is an immune-related inflammatory activity involving the extraocular muscles with a female preponderance [116]. Although rare, bilateral sequential tracheitis has also been reported [117].…”

Section: Orbit Extraocular Muscles and Refractive Shiftmentioning

confidence: 99%

“…Although rare, bilateral sequential tracheitis has also been reported [117]. Signs and symptoms may include restricted gaze, pain in eye movement diplopia, headache, periorbital edema, and ocular hypertension [116]. It is usually misdiagnosed as orbital cellulitis, as a diagnosis of exclusion a thorough serologic screening, adequate ophthalmic evaluation ultrasound, computerized tomography (CT), and magnetic resonance imaging (MRI) scan are usually required.…”

Section: Orbit Extraocular Muscles and Refractive Shiftmentioning

confidence: 99%

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Unveiling Ocular Manifestations in Systemic Lupus Erythematosus

Musa,

Chukwuyem,

Ojo

et al. 2024

JCM

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Systemic Lupus Erythematosus (SLE) is a complex autoimmune disorder characterized by immune dysregulation and multi-organ involvement. In this concise brief review, we highlight key insights into Ocular Systemic Lupus Erythematosus (SLE), an intricate autoimmune disorder with diverse organ involvement. Emphasizing the formation of autoantibodies and immune complex deposition, we delve into the inflammation and damage affecting ocular structures. Clinical presentations, ranging from mild dry eye syndrome to severe conditions like retinal vasculitis, necessitate a comprehensive diagnostic approach, including clinical exams, serological testing, and imaging studies. Differential diagnosis involves distinguishing SLE-related ocular manifestations from other autoimmune and non-inflammatory ocular conditions. The multidisciplinary management approach, involving rheumatologists, ophthalmologists, and immunologists, tailors treatment based on ocular involvement severity, encompassing corticosteroids, immunosuppressive agents, and biologics. Follow-up is crucial for monitoring disease progression and treatment response. Future perspectives revolve around advancing molecular understanding, refining diagnostic tools, and exploring targeted therapies. Novel research areas include genetic factors, microbiome composition, and biotechnology for tailored and effective SLE ocular treatments.

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Section: Orbit Extraocular Muscles and Refractive Shiftmentioning

confidence: 99%

Section: Orbit Extraocular Muscles and Refractive Shiftmentioning

confidence: 99%