Orbital Metastasis from Urothelial Carcinoma of the Urinary Bladder

Lin, Huaiying; Chang, Chang-Hsien; Li, Weiming; Hsiao, Hsi‐Lin; Chang, Tsung‐Kun; Wu, Wen‐Jeng; Huang, Chun‐Hsiung

doi:10.1016/s1607-551x(09)70380-8

Cited by 8 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, eye structures with the highest vascular supply are more likely affected, with an incidence from 1 to 13% (2). Breast cancer is the most common primary tumor metastasizing to the eye, followed in order of frequency by: Lung cancer, gastrointestinal tumors, and less commonly, thyroid, prostate, kidney, testicles, pancreatic, ovarian and liver cancer (4). Eye metastases comprise both orbital (bone, muscle and fat) and ocular (mainly uveal) localizations (5,6).…”

Section: Introductionmentioning

confidence: 99%

Urothelial bladder carcinoma metastasizing to the eye: A systematic review and case report

et al. 2018

View full text Add to dashboard Cite

The eye is a rare site for disseminated malignancies; nevertheless, several tumors may metastasize to ocular structures. Few cases of urothelial and bladder cancer with eye involvement have been described in the literature thus far. The rarity of metastatic ocular localization implies an accurate differential diagnosis among the possible primary tumor sites. However, a specific diagnostic algorithm is not currently available, nor a defined therapeutic approach. Eye metastases are associated with advanced disease and poor prognosis. Physicians should be made aware of the possibility of eye involvement in patients with a past medical history of urothelial bladder cancer associated with ocular symptoms. The present case reports discusses the first documented case, to the best of our knowledge, of an urothelial bladder cancer metastasizing to the retro bulbar region that infiltrates the lacrimal gland. Furthermore, the report provides a systematic qualitative review of the current literature on eye metastases from urothelial bladder cancer using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.

show abstract

Section: Introductionmentioning

confidence: 99%

Urothelial bladder carcinoma metastasizing to the eye: A systematic review and case report

et al. 2018

View full text Add to dashboard Cite

show abstract

Bilaterale periorbitale Metastasen eines Urothelkarzinoms der Harnblase

Fierlbeck

Helmbold

2010

Hautarzt

View full text Add to dashboard Cite

Bladder cancers account about 3% of malignant tumors and often metastasize to regional lymph nodes, liver, lungs and skeleton. Metastases in the area of the orbital region are very rare. When eyelid swelling, proptosis, diplopia, or ocular pain occurs, an underlying neoplastic process should always be suspected. Due to the rapid progression of orbital metastases, diagnosis and early initiation of palliative therapy is important.

show abstract