Orbital Lymphoma

Esmaeli, Bita; Faustina, Misha

doi:10.1007/0-387-27086-8_13

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…POLs are those where the orbit is the isolated extranodal site. In contrast, secondary orbital lymphomas are those where the orbit is secondarily involved in a previously diagnosed case of NHL or simultaneously occurring in a case of any other systemic lymphoma 10 . In our study, 50% (8 of 16) of the cases qualified as POL.…”

Section: Discussioncontrasting

confidence: 50%

“…The majority (85%‐90%) of lymphomas are low‐grade small cell lymphomas with extranodal MZL of the mucosa‐associated lymphoid tissue (MALT) subtype being the most common subtype. MALT lymphomas have a unique property of homing to epithelial tissues and mucosal tissues, which may be the reason for bilateral involvement 10 , 11 . POLs are those where the orbit is the isolated extranodal site.…”

Section: Discussionmentioning

confidence: 99%

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The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

et al. 2020

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Background Orbital hematolymphoid lesions are rare and usually encountered in elderly patients. Orbital lesions are not easy to biopsy: hence fine needle aspiration cytology (FNAC) can be a very good diagnostic modality for these lesions. Materials and Methods Cases of orbital masses subjected to FNAC dating from 2013 to 2020 were retrieved from our archives. A total of 16 cases with biopsy confirmation were included. All clinical details, the type of procedure, details of the immunocytochemistry (ICC) performed on smear, follow‐up biopsy, and their haematological work‐up were analysed in detail. Results Sixteen biopsy‐confirmed cases had been diagnosed as orbital haematolymphoid lesions on cytomorphology and further categorised with ancillary studies including ICC. In twelve instances, the cytology impression was congruent with the histopathological diagnosis and eight of the sixteen cases (50%) proved to be primary orbital lymphoma. Four were secondary orbital lymphomas and the remaining four included one case each of plasmacytoma, myeloid sarcoma, Rosai‐Dorfman disease and angiolymphoid hyperplasia with eosinophilia. Conclusion FNAC is a minimally invasive procedure for diagnosing most of the haematolymphoid orbital lesions and it has a rapid turnaround time. The accuracy of cytomorphology combined with ICC on smears/cell blocks can be as good as a biopsy for exact categorisation. Additionally, aspirate smears are preferred samples for cytogenetics compared to formalin‐fixed tissue blocks, as molecular cytogenetics techniques are frequently employed for diagnostic, prognostic, and therapeutic purposes.

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Section: Discussioncontrasting

confidence: 50%

Section: Discussionmentioning

confidence: 99%

The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

et al. 2020

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Ocular lymphoma: overcoming a diagnostic challenge with an endoscopic sinus approach

et al. 2023

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Value of Positron Emission Tomography in Staging Ocular Adnexal Lymphomas and Evaluating Their Response to Therapy

Gayed¹,

Eskandari²,

McLaughlin³

et al. 2007

Ophthalmic Surg Lasers Imaging Retina

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<H4>BACKGROUND AND OBJECTIVE</H4> <P>An observational case series to assess the value of positron emission tomography (PET) in staging ocular adnexal lymphomas and evaluating their response to therapy.</P> <H4>PATIENTS AND METHODS</H4> <P>The clinical records of 16 consecutive patients with ocular adnexal lymphoma for whom pretreatment and posttreatment PET scans and corresponding computed tomography (CT) and magnetic resonance imaging (MRI) scans were available were compared.</P> <H4>RESULTS</H4> <P>Pretreatment PET scans demonstrated fluorine 18-fluorodeoxyglucose (FDG) positive lesions in 15 orbits of 12 patients. In 1 patient with low-grade follicular lymphoma of the orbit, PET revealed an additional focus of lymphoma in the deltoid muscle that was missed on clinical examination and conventional radiography. All of the posttreatment PET scans showed complete resolution of FDG uptake, suggesting good response to therapy. However, posttreatment CT and MRI scans demonstrated residual masses in 3 patients.</P> <H4>CONCLUSIONS</H4> <P>PET is valuable for initial staging of ocular adnexal lymphomas and may be a good adjunct to conventional imaging in evaluation of response to therapy.</P> <P>[<CITE>Ophthalmic Surg Lasers Imaging</CITE> 2007;38:319-325.]</P> <H4>AUTHORS</H4> <P>From the Department of Nuclear Medicine (IG); the Section of Ophthalmology (MFE, RD, BE); and the Department of Lymphoma and Myeloma (PM, BP), The University of Texas M. D. Anderson Cancer Center, Houston, Texas.</P> <P>Accepted for publication January 9, 2007.</P> <P>Address correspondence to Bita Esmaeli, MD, Section of Ophthalmology, M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Unit 441, Houston, TX 77030.</P>

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Orbital Lymphoma

Cited by 4 publications

References 31 publications

The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

Ocular lymphoma: overcoming a diagnostic challenge with an endoscopic sinus approach

Value of Positron Emission Tomography in Staging Ocular Adnexal Lymphomas and Evaluating Their Response to Therapy

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